Results 21 to 30 of about 63,187 (253)

VLDL-TG secretion in Lipg^-/- mice.

, 2021
A. Plasma triglycerides in mice at the indicated timepoints following intraperitoneal injection of poloxamer P407, a competitive inhibitor of LPL activity. Plasma TGs were measured by colorimetric biochemical assays. B. VLDL-TG secretion rates calculated
Papasani V. Subbaiah (232673), Daniel J. Rader (7658096), Takashi Kuwano (8746116), Derek Klarin (2079340), Dhavamani Sugasini (4579258), Cecilia Vitali (2503018), Michael G. Levin (9499397), Akhil Pampana (11457970), Jeffrey T. Billheimer (11457976), Sumeet A. Khetarpal (11457967), Pradeep Natarajan (819434), John S. Millar (11457973), Joseph Park (2032012)   +12 more
core   +1 more source

FAM3A Inhibits Plasma Triglyceride Levels via Microvasculature-Involved Enhancement of VLDL-Triglyceride Hydrolysis and Lipid Uptake. [PDF]

FASEB J
FAM3A enhances the PPARα signaling, leading to upregulated expression of lipid transporters including CD36 and TCF15. The upregulated CD36 and TCF15 enhance FA uptake and trans‐endothelial delivery in MVECs. Meanwhile, FAM3A‐enhanced PPARα signaling also increases LPL expression in myocytes and LPL position in lumen side of microvasculature to promote ...
Song X, Xiang W, Xian X, Yuan L, Wu J, Qiu B, Yang D, Zheng Y.   +7 more
europepmc   +2 more sources

Effects of Deltamethrin and Endosulfan on the Hepatic Markers and Neurobehavioural Alterations in Japanese Quail (Coturnix japonica). [PDF]

Vet Med Sci
Japanese quail were exposed to combined low or high doses of deltamethrin and endosulfan by daily oral gavage for 3 weeks. Co‐exposure produced dose‐dependent hepatotoxicity and metabolic disruption, with elevated AST (aspartate aminotransferase), ALP (alkaline phosphatase), LDL, VLDL and cholesterol alongside reduced body and kidney weights.
Malik S, Ahmad S, Naeem M, Bibi I, Majid MS, Sadia H, Riaz S, Siddik MAB.   +7 more
europepmc   +2 more sources

To Investigate the Effect of Dyslipidemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus—In the Tertiary Care Center. A Study Protocol

Journal of Pharmacy and Bioallied Sciences
Introduction: Type 2 DM is the most common type of diabetes and it is characterized by a combination of insulin resistance and relative insulin shortage caused by pancreatic beta cell failure.
Akansha Singh, Ranjit S. Ambad, Roshan Kumar Jha, Rakesh Kumar Jha   +3 more
doaj   +1 more source

α-Tocopherol Reduces VLDL Secretion through Modulation of Intracellular ER-to-Golgi Transport of VLDL [PDF]

, 2023
Avoiding hepatic steatosis is crucial for preventing liver dysfunction, and one mechanism by which this is accomplished is through synchronization of the rate of very low-density lipoprotein (VLDL) synthesis with its secretion.
Ryan Clay, Clay, Ryan, Siddiqi, Shadab A., Shaila Siddiqi, Siddiqi, Shaila, Shadab A. Siddiqi   +5 more
core   +1 more source

Practical Approaches to Managing Dyslipidemia in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

Journal of Lipid and Atherosclerosis
Dyslipidemia is a major risk factor for cardiovascular disease, and its impact may be exacerbated when accompanied by metabolic dysfunction-associated steatotic liver disease (MASLD).
Fernando Bril, Gabriela Berg, Magali Barchuk, Juan Patricio Nogueira   +3 more
doaj   +1 more source

Moderate dyslipoproteinemia induced inflammation and remodeling HDL and VLDL particles in post-renal transplant patients

Current Issues in Pharmacy and Medical Sciences, 2017
The aim of this paper was to examine whether moderate dyslipoproteinemia can cause an increase of hsCRP and LPO levels in Tx patients who had received immunosuppressive therapy and were without acute inflammatory diseases. Herein, the lipid levels, hsCRP,
Kimak Elzbieta, Baranowicz-Gaszczyk Iwona, Bialopiotrowicz Tomasz   +2 more
doaj   +1 more source

Resistance of a very low density lipoprotein subpopulation from familial dysbetalipoproteinemia to in vitro lipolytic conversion to the low density lipoprotein density fraction.

Journal of Lipid Research, 1983
In vitro lipolysis of very low density lipoprotein (VLDL) from normolipidemic and familial dysbetalipoproteinemic plasma by purified bovine milk lipoprotein lipase was studied using the combined single vertical spin and vertical autoprofile method of ...
B H Chung, J P Segrest
doaj   +1 more source

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism

Journal of Lipid Research, 2008
Cholesteryl ester transfer protein (CETP) inhibition leads to changes in lipoprotein metabolism. We studied the effect of the CETP inhibitor torcetrapib on VLDL apolipoprotein E (apoE) metabolism.
John S. Millar, Margaret E. Brousseau, Margaret R. Diffenderfer, P. Hugh R. Barrett, Francine K. Welty, Jeffrey S. Cohn, Aisha Wilson, Megan L. Wolfe, Chorthip Nartsupha, Peter M. Schaefer, Andres G. Digenio, James P. Mancuso, Gregory G. Dolnikowski, Ernst J. Schaefer, Daniel J. Rader   +14 more
doaj   +1 more source

Plasma clearance and biodistribution of oxidatively modified 99mTc-ß-VLDL in rabbits

Brazilian Journal of Medical and Biological Research, 1997
The biodistribution and removal from plasma (measured as fractional clearance rate, FCR, per hour) of native and oxidatively modified 99mtechnetium-labeled ß-very low density lipoprotein (99mTc-ß-VLDL) were investigated in hypercholesterolemic (HC) and ...
E.L. Silva, J.C. Meneghetti, I.J.C Coelho, D.S.P Abdalla   +3 more
doaj   +1 more source