Results 41 to 50 of about 63,187 (253)

Effects of exercise on VLDL-triglyceride oxidation and turnover

, 2011
Lipids are important substrates for oxidation at rest and during exercise. Aerobic exercise mediates a delayed onset decrease in total and VLDL-triglyceride (TG) plasma concentration.
Esben Sondergaard, Søren Nielsen, Iben Rahbek, Lars P. Sørensen, Jens S. Christiansen, Lars C. Gormsen, Michael D. Jensen   +6 more
core   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

VLDL Selection into VLDL Transport Vesicle (VTV) is Regulated by CideB

The FASEB Journal, 2012
Very low‐density lipoproteins (VLDLs) circulating in the plasma play a key role in the development of atherosclerosis. VLDLs are synthesized and secreted by the liver. The rate‐determining step in VLDL secretion is their transport from the endoplasmic reticulum (ER) to the Golgi, which is facilitated by a distinct vesicle, the VTV.
Samata Tiwari, Shaila Siddiqi, Arul Mani, Shadab A. Siddiqi   +3 more
openaire   +1 more source

Adipocytokines and VLDL Metabolism [PDF]

Diabetes, 2005
We investigated the relationship of plasma adipocytokine concentrations with VLDL apolipoprotein B (apoB)-100 kinetics in men. Plasma adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) concentrations were measured using enzyme immunoassays and insulin resistance by homeostasis model assessment (HOMA) score in 41 ...
Theodore W.K. Ng, Gerald F. Watts, Maryam S. Farvid, Dick C. Chan, P. Hugh R. Barrett   +4 more
openaire   +1 more source

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.

Journal of Lipid Research, 1996
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this study, a
J Bjorkegren, C J Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe   +8 more
doaj   +1 more source

Effect of IGF-I therapy on VLDL apolipoprotein B100 metabolism in type 1 diabetes mellitus

, 2002
Abnormal lipid metabolism may be related to the increased cardiovascular risk in type 1 diabetes. Secretion and clearance rates of very low density lipoprotein (VLDL) apolipoprotein B100 (apoB) determine plasma lipid concentrations.
Umpleby, A Margot, Russell-Jones, D L, Wierzbicki, Anthony S, Russell-Jones, David L, Albany, Elaine, Lumb, P J, Albany, E, Sönksen, Peter H, Christ, Emanuel R, Carroll, Paul V, Wierzbicki, A S, Christ, E R, Umpleby, A M, Sonksen, P H, Lumb, Peter J, Carroll, P V, Carroll PV, Christ, Emanuel, Umpleby AM, Wierzbicki AS, Albany E, Russell-Jones DL, Christ ER, Lumb PJ, Sönksen PH   +24 more
core   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

Journal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry, T Olivecrona, R J Deckelbaum, S Eisenberg   +3 more
doaj   +1 more source

Fasting VLDL lipolysis products attenuate LPS-induced TNFα release.

, 2013
(A-B) Monocytes treated with fasting or postprandial VLDL lipolysis products and LPS exhibited dose-dependent attenuation of TNFα secretion (n = 6).
John C. Rutledge (25389), Madhu S. Budamagunta (297273), Laura J. den Hartigh (297271), John C. Voss (169063), Jitka Petrlova (131452), Sarada D. Tetali (297274), Jens O. Lagerstedt (297275), Robin Altman (169023), Romobia Hutchinson (297272)   +8 more
core   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source