Results 61 to 70 of about 59,863 (274)
—The differential effects of overexpression of human apolipoprotein (apo) E3 on plasma cholesterol and triglyceride metabolism were investigated in transgenic rabbits expressing low (<10 mg/dL), medium (10 to 20 mg/dL), or high (>20 mg/dL) levels ...
Walter J. Brecht +5 more
core +1 more source
New therapeutic options for metabolic‐associated steatotic liver disease
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley +1 more source
The livers of both baboons and rhesus monkeys fed a high fat, high cholesterol diet secreted very low density lipoproteins (VLDL) that were enriched in cholesteryl ester and apoe as compared to VLDL secreted by the livers of chow-fed animals. Stimulation
P A Soltys +7 more
doaj +1 more source
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi +2 more
wiley +1 more source
High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDLs⃞
Withdrawing growth factors or serum from endothelial cells leads to the activation of effector caspases 3 and 7, resulting in apoptotic cell death. HDL protects against caspase induction through sphingosine-1-phosphate (S1P) receptors.
Mirta Mihovilovic +4 more
doaj +1 more source
Regulation of VLDL production in the liver [PDF]
The aim of this thesis is to summarize current knowledge about VLDL (very low density lipoprotein) assembly. In the first part of this thesis basic characteristics of lipids and lipoproteins are described.
Jirátová, Markéta
core
Abstract Saturated fats (SFAs) play a complex role in health; therefore, their intake has been a topic of debate in the field of nutrition science. Therefore, this article emphasizes the importance of a balanced diet rather than SFA, considering genetic and metabolic differences, and advocates for the reconsideration of dietary guidelines based on the ...
Akash Kumar +7 more
wiley +1 more source
Cholesteryl ester transfer protein (CETP) mediates the transfer of HDL cholesteryl esters for triglyceride (TG) in VLDL/LDL. CETP inhibition, with anacetrapib, increases HDL-cholesterol, reduces LDL-cholesterol, and lowers TG levels. This study describes
John S. Millar +20 more
doaj +1 more source
The VLDL particle secretion is reduced upon LXR activation.
histograms were calculated from the acceptable sets to determine the density of trajectories during the treatment period. A darker color represents a higher density of trajectories in that specific region and time point.
Maaike H. Oosterveer (262779) +5 more
core +1 more source
A nutrient‐dense grain, proso millet is well‐known for its high protein content and vital amino acids. It is high in fiber, vitamins, and minerals and has many health advantages, including promoting heart health, enhancing digestion, and helping with weight management.
Sangeeta Yadav +3 more
wiley +1 more source

