Results 51 to 60 of about 59,863 (274)

Susceptibility of VLDL to oxidation in patients on regular haemodialysis

, 1997
Oxidation of VLDL in vitro increases macrophage uptake and promotes foam cell formation, and the dyslipidaemia of chronic renal failure is characterised by an increase in VLDL. However, little information is available with regard to the susceptibility of
Young, Ian, Trimble, Elizabeth, Loughrey, C.M., McNamee, P.T., McEneny, Jane   +4 more
core   +3 more sources

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Receptor-mediated uptake of hypertriglyceridemic very low density lipoproteins by normal human fibroblasts

Journal of Lipid Research, 1982
Our previous studies showed that very low density lipoproteins, Sf 60-400 (VLDL), from hypertriglyceridemia subjects, but not VLDL from normolipemic subjects, suppress HMG-CoA reductase activity in normal human fibroblasts.
S H Gianturco, F B Brown, A M Gotto, Jr, W A Bradley   +3 more
doaj   +1 more source

VLDL Selection into VLDL Transport Vesicle (VTV) is Regulated by CideB

The FASEB Journal, 2012
Very low‐density lipoproteins (VLDLs) circulating in the plasma play a key role in the development of atherosclerosis. VLDLs are synthesized and secreted by the liver. The rate‐determining step in VLDL secretion is their transport from the endoplasmic reticulum (ER) to the Golgi, which is facilitated by a distinct vesicle, the VTV.
Samata Tiwari, Shaila Siddiqi, Arul Mani, Shadab A. Siddiqi   +3 more
openaire   +1 more source

Apolipoprotein VLDL-II mediates VLDL particle size in laying hens -synergism with microsomal triglyceride transfer protein functionality

, 2021
鳥類胚胎營養來源完全依賴蛋黃中脂質供應，因此母鳥於產蛋期間需提供更多脂質以形成蛋黃。產蛋母鳥之VLDL與未產蛋母鳥有以下幾點不同:1) 較小之粒徑以通過顆粒細胞基底膜，2) 較高的三酸甘油酯與磷脂比率，3) VLDL上鑲嵌著鳥類所獨有，受到雌激素誘導生成的載脂蛋白Apolipoprotein VLDL-II，此蛋白質已被證實可干擾VLDL脂蛋白分解酶作用(Lipoprotein lipase, LPL)，保護VLDL於血液循環中運輸，完整的進入濾泡蓄積成蛋黃。但apo VLDL ...
Yu-Lin Ye, 葉宥麟
core  

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice

Journal of Lipid Research, 2000
In addition to its role in the uptake of apolipoprotein B (apoB)-containing lipoproteins, apoE promotes hepatic very low density lipoprotein-triglyceride (VLDL-TG) production in animal models.
Cyrille Maugeais, Uwe J.F. Tietge, Kazuhisa Tsukamoto, Jane M. Glick, Daniel J. Rader   +4 more
doaj   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects

Journal of Lipid Research, 2010
The effect of apolipoprotein (apo) E genotype on apoB-100 metabolism was examined in three normolipidemic apoE2/E2, five type III hyperlipidemic apoE2/E2, and five hyperlipidemic apoE3/E2 subjects using simultaneous administration of 131I-VLDL and 125I ...
Esther M.M. Ooi, Edward D. Janus, Susan J. Grant, Lucia M.T. Sinclair, P. Hugh R.Barrett   +4 more
doaj   +1 more source

APOC1-Associated VLDL-Pathway Dysregulation in Papillary Thyroid Carcinoma: A Reproducible Cross-Cohort Transcriptomic Signature Associated With the Diagnostic-to-Treatment Interval. [PDF]

Chem Biol Drug Des
Across four independent thyroid cancer cohorts, multi‐omics analysis identifies a reproducible APOC1–LPL–VLDLR lipid‐pathway signature linked to the preoperative diagnostic‐to‐treatment interval, nominating triglyceride‐rich lipoprotein metabolism as a candidate window for monitoring and a potential metabolic axis in papillary thyroid carcinoma ...
Li Y, Meng G, Peng M, Chen G, Zhang YP.
europepmc   +2 more sources