Results 71 to 80 of about 59,863 (274)

Oxidized VLDL Induces Less Triglyceride Accumulation in J774 Macrophages Than Native VLDL Due to an Impaired Extracellular Lipolysis

, 2000
—The present study examined the relative contributions of the different pathways by which oxidatively modified VLDL (oxVLDL) promotes the uptake and intracellular accumulation of lipids in J774 macrophages.
Leonie C. van Vark, Vivian E. H. Dahlmans, Johanna E. M. Groener, Miek C. Jong, Wendy L. Hendriks, Louis M. Havekes   +5 more
core   +2 more sources

Apoprotein E mediates the interaction of beta-VLDL with macrophages.

Journal of Lipid Research, 1987
beta-Very low density lipoproteins (beta-VLDL) isolated from cholesterol-fed rhesus monkeys stimulated cholesteryl ester synthesis and accumulation in mouse peritoneal macrophages. The apoprotein specificity and requirement for the cell surface uptake of
S R Bates, B A Coughlin, T Mazzone, J Borensztajn, G S Getz   +4 more
doaj   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

Heparan sulfate proteoglycans mediate internalization and degradation of beta-VLDL and promote cholesterol accumulation by pigeon macrophages

Journal of Lipid Research, 1997
Pigeon and rabbit beta-migrating very low density lipoprotein (beta-VLDL) are similar in size and composition, yet rabbit beta-VLDL consistently stimulates greater cholesteryl ester accumulation in pigeon peritoneal macrophages than does pigeon beta-VLDL.
T Seo, R W St Clair
doaj   +1 more source

A novel role for CD36 in VLDL-enhanced platelet activation [PDF]

, 2003
Type 2 diabetes is characterized by increased plasma triglyceride levels and a fourfold increase in ischemic heart disease, but the mechanism is unclear. CD36 is a receptor/transporter that binds fatty acids of lipoproteins.
Aitman, T.J., Baglin, T.P., T. P. Baglin, N. A. Englyst, J. M. Taube, Byrne, C.D., Englyst, N.A., T. J. Aitman, Taube, J.M., C. D. Byrne   +9 more
core   +1 more source

Lipoprotein lipase- and hepatic triglyceride lipase-promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism

Journal of Lipid Research, 2000
Apolipoprotein E (apoE) is the primary recognition signal on triglyceride-rich lipoproteins responsible for interacting with low density lipoprotein (LDL) receptors and LDL receptor-related protein (LRP).
Jheem D. Medh, Glenna L. Fry, Susan L. Bowen, Stacie Ruben, Howard Wong, David A. Chappell   +5 more
doaj   +1 more source

LDL, scavenger, and beta-VLDL receptors on aortic endothelial cells.

, 1984
Primary and first passage aortic endothelial cells were shown to possess a high affinity receptor for beta-migrating very low density lipoproteins (beta-VLDL) distinct from the low density lipoprotein (LDL) receptor and scavenger receptor on these cells.
P A Edwards, A M Fogelman, J A Berliner, B J Van Lenten, D P Baker, C Kean   +5 more
core   +1 more source

Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics

Journal of Lipid Research, 2007
To gain insight into the mechanisms regulating plasma lipid homeostasis, FFA, VLDL-triglyceride (TG), and VLDL-apolipoprotein B-100 (apoB-100) kinetics are commonly assessed using stable isotope-labeled tracer methods.
Magkos Faidon, Bruce W. Patterson, Mittendorfer Bettina   +2 more
doaj   +1 more source

Effects of exercise on VLDL-triglyceride oxidation and turnover

, 2011
Lipids are important substrates for oxidation at rest and during exercise. Aerobic exercise mediates a delayed onset decrease in total and VLDL-triglyceride (TG) plasma concentration.
Esben Sondergaard, Søren Nielsen, Iben Rahbek, Lars P. Sørensen, Jens S. Christiansen, Lars C. Gormsen, Michael D. Jensen   +6 more
core   +1 more source

Progression of Chronic Kidney Disease Affects HDL Impact on Lipoprotein Lipase (LPL)-Mediated VLDL Lipolysis Efficiency

Kidney & Blood Pressure Research, 2018
Background/Aims: Hypertriglyceridaemia (HTG) and reduction and dysfunction of high density lipoprotein (HDL) are common lipid disturbances in chronic kidney disease (CKD). HTG in CKD is caused mainly by the decreased efficiency of lipoprotein lipase (LPL)
Agnieska Ćwiklińska, Monika Cackowska, Ewa Wieczorek, Ewa Król, Robert Kowalski, Agnieszka Kuchta, Barbara Kortas-Stempak, Anna Gliwińska, Kamil Dąbkowski, Justyna Zielińska, Alicja Dębska-Ślizień, Maciej Jankowski   +11 more
doaj   +1 more source