Results 71 to 80 of about 63,187 (253)

VLDL Satisfiability and Model Checking via Tree Automata [PDF]

, 2018
We present novel algorithms solving the satisfiability problem and the model checking problem for Visibly Linear Dynamic Logic (VLDL) in asymptotically optimal time via a reduction to the emptiness problem for tree automata with Büchi acceptance.
Weinert, Alexander
core   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Apoprotein E mediates the interaction of beta-VLDL with macrophages.

Journal of Lipid Research, 1987
beta-Very low density lipoproteins (beta-VLDL) isolated from cholesterol-fed rhesus monkeys stimulated cholesteryl ester synthesis and accumulation in mouse peritoneal macrophages. The apoprotein specificity and requirement for the cell surface uptake of
S R Bates, B A Coughlin, T Mazzone, J Borensztajn, G S Getz   +4 more
doaj   +1 more source

Liver Proteomic Alterations Induced by Chronic Fluoride Exposure in Type 2 Diabetic Mice: An Exploratory Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Water fluoridation is recognized as one of the major public health achievements of the 20th century due to its effectiveness in reducing dental caries. Recommended fluoride concentrations in drinking water (0.7–1.5 mgF/L) aim to maximize dental benefits while minimizing adverse effects.
Laura Ribeiro, Heloisa Aparecida Barbosa da Silva Pereira, Juliana Sanches Trevizol, Aislan Quintiliano Delgado, Aline Dionízio, Tamara Teodoro Araujo, Tânia Mary Cestari, José Roberto Bosqueiro, Marília Afonso Rabelo Buzalaf   +8 more
wiley   +1 more source

Heparan sulfate proteoglycans mediate internalization and degradation of beta-VLDL and promote cholesterol accumulation by pigeon macrophages

Journal of Lipid Research, 1997
Pigeon and rabbit beta-migrating very low density lipoprotein (beta-VLDL) are similar in size and composition, yet rabbit beta-VLDL consistently stimulates greater cholesteryl ester accumulation in pigeon peritoneal macrophages than does pigeon beta-VLDL.
T Seo, R W St Clair
doaj   +1 more source

Hypocholesterolemia in liver and cardiovascular disease: Friend or foe? [PDF]

J Intern Med
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Flagiello V, Barreby E, Vespasiani-Gentilucci U, Romeo S.   +3 more
europepmc   +2 more sources

Establishment and Application of a Quantitative Lipemia Index as a Novel Indicator for Assessing Lipemic Interference in Clinical Chemistry

Journal of Clinical Laboratory Analysis, EarlyView.
A rigorously validated quantitative lipemia index (LI) assay was established for direct serum turbidity measurement. This standardized LI metric demonstrated significantly stronger correlation with lipemic interference (rs = 0.822) than conventional triglyceride concentration (rs = 0.770), consistent with its direct measurement of optical turbidity ...
Haifeng Xie, Shuhua Bao, Pengcheng Tong, Peng Li, Zhe Shen, Jinlong Wei   +5 more
wiley   +1 more source

Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics

Journal of Lipid Research, 2007
To gain insight into the mechanisms regulating plasma lipid homeostasis, FFA, VLDL-triglyceride (TG), and VLDL-apolipoprotein B-100 (apoB-100) kinetics are commonly assessed using stable isotope-labeled tracer methods.
Magkos Faidon, Bruce W. Patterson, Mittendorfer Bettina   +2 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

The role of apolipoprotein VLDL-II in regulating VLDL particle size profile

, 2019
鳥類產蛋期時，因肝臟受到雌性素 (estradiol) 的作用下大量產生三酸甘油脂 (Triglyceride, TG)，血漿中出現較小粒徑VLDL脂蛋白顆粒，此時VLDL以apo B-100及鳥類特有的載脂蛋白 (apolipoprotein VLDL-II, apo VLDL-II) 所組成，產生富含TG的VLDL運輸至卵巢卵母細胞中，堆積形成蛋黃以提供胚胎發育所用，故稱為VLDLy。產蛋期母雞apoVLDL-II與較小粒徑VLDLy的同時出現，因沒有直接的證據證明，使得apoVLDL ...
鍾正玗, Cheng-Yu Chung
core