Results 91 to 100 of about 59,863 (274)

Studies on the metabolism of apolipoprotein B in hypertriglyceridemic subjects using simultaneous administration of tritiated leucine and radioiodinated very low density lipoprotein.

Journal of Lipid Research, 1990
To study the metabolic pathways of apolipoprotein B (apoB), a series of studies were carried out in which both radioiodinated very low density lipoproteins (VLDL) and tritiated leucine were simultaneously injected into three hypertriglyceridemic subjects.
WF Beltz, YA Kesäniemi, NH Miller, WR Fisher, SM Grundy, LA Zech   +5 more
doaj   +1 more source

The role of apolipoprotein VLDL-II in regulating VLDL particle size profile

, 2019
鳥類產蛋期時，因肝臟受到雌性素 (estradiol) 的作用下大量產生三酸甘油脂 (Triglyceride, TG)，血漿中出現較小粒徑VLDL脂蛋白顆粒，此時VLDL以apo B-100及鳥類特有的載脂蛋白 (apolipoprotein VLDL-II, apo VLDL-II) 所組成，產生富含TG的VLDL運輸至卵巢卵母細胞中，堆積形成蛋黃以提供胚胎發育所用，故稱為VLDLy。產蛋期母雞apoVLDL-II與較小粒徑VLDLy的同時出現，因沒有直接的證據證明，使得apoVLDL ...
鍾正玗, Cheng-Yu Chung
core  

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Familial LCAT Deficiency and Low HDL-C Levels: In silico Characterization of Two Rare LCAT Missense Mutations

The Application of Clinical Genetics
Sebastian Ciro Acosta,1 Lorena Díaz-Ordóñez,1,2 Juan David Gutierrez-Medina,1,3 Yisther Katherine Silva-Cuero,1,2 Luis Guillermo Arango-Vélez,4,5 Andrés Octavio García-Trujillo,4,5 Harry Pachajoa1,2,6 1Centro de Investigaciones en Anomalias Congenitas y ...
Ciro Acosta S, Díaz-Ordóñez L, Gutierrez-Medina JD, Silva-Cuero YK, Arango-Vélez LG, García-Trujillo AO, Pachajoa H   +6 more
doaj  

Altered apolipoprotein B metabolism in very low density lipoprotein from lovastatin-treated guinea pigs.

Journal of Lipid Research, 1994
Previous studies have shown that treatment of guinea pigs with lovastatin alters the composition and the metabolic properties of circulating low density lipoprotein (LDL).
L F Berglund, W F Beltz, R L Elam, J L Witztum   +3 more
doaj   +1 more source

Alpha-Tocopherol Reduces VLDL Secretion Through Modulation of the VLDL Transport Vesicle

, 2019
The liver distributes serum triacylglycerol (TAG) via the very low-density lipoprotein (VLDL), and an increase in VLDL production may result in hyperlipidemia.
Clay, Ryan
core  

The Role and Assessment of Lipid Profile in Patients With a Chronic Total Coronary Occlusion

Lipids, EarlyView.
This review summarized evidence on lipid profiles in CTO patients, non‐CTO patients, and healthy individuals, and examined the reported associations between lipid parameters, collateral channel formation, and clinical outcomes. Several key findings emerged from the present study.
Karol Sadowski, Dominika Tomkiel, Roel Hoek, Ruben W. de Winter, Nick S. Nurmohamed, Bimmer E. P. M. Claessen, Niels J. Verouden, Alexander Nap, Sebastiaan A. Kleijn, Mariusz Tomaniak, Yvemarie B. O. Somsen, Paul Knaapen   +11 more
wiley   +1 more source

Energy expenditure, insulin, and VLDL-triglyceride production in humans

Journal of Lipid Research, 2006
Hypertriglyceridemia is considered a cardiovascular risk factor in diabetic and nondiabetic subjects. In this study, we aimed to determine potential regulators of very low density lipoprotein-triglyceride (TG) production.
Lars C. Gormsen, Michael D. Jensen, Ole Schmitz, Niels Møller, Jens S. Christiansen, Søren Nielsen   +5 more
doaj   +1 more source

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Isolation and properties of nascent lipoproteins from highly purified rat hepatocytic Golgi fractions

Journal of Lipid Research, 1991
Two procedures were used to isolate hepatocytic Golgi fractions from rat liver. One procedure yields a light Golgi fraction (GF1 + 2) and the other “intact” stacks of cisternae.
RL Hamilton, A Moorehouse, RJ Havel
doaj   +1 more source