Results 111 to 120 of about 63,187 (253)

Reduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in mice

Journal of Lipid Research, 2009
The nuclear liver X receptor (LXR) regulates multiple aspects of cholesterol, triacylglycerol (TG), and carbohydrate metabolism. Activation of LXR induces the expression of genes encoding enzymes involved in de novo lipogenesis (DNL) resulting in hepatic
Aldo Grefhorst, Elizabeth J. Parks
doaj   +1 more source

CETP expression reverses the reconstituted HDL-induced increase in VLDL

, 2011
Human data suggest that reconstituted HDL (rHDL) infusion can induce atherosclerosis regression. Studies in mice indicated that rHDL infusion adversely affects VLDL levels, but this effect is less apparent in humans.
Stroes, E.S., Berbée, J.F.P., Romijn, J.A., Wang, Y., Rensen, P.C.N., Smit, J.W.A., Havekes, L.M.   +6 more
core  

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Causal Effects of Lipids-Related Metabolites on Androgenic Alopecia: A Mendelian Randomization Study

Clinical, Cosmetic and Investigational Dermatology
Lingbo Bi,* Chaofan Wang,* Yimei Du,* Changpei Lu, Min Zhao, Yunbu Ding, Weiling Sun, Weixin Fan Department of Dermatology, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, People’s Republic of ...
Bi L, Wang C, Du Y, Lu C, Zhao M, Ding Y, Sun W, Fan W   +7 more
doaj  

Human breast milk lipoproteins: A preliminary biochemical characterization

Experimental Physiology, EarlyView.
Abstract Human breast milk (BM) is an essential fluid for infant development, with a dynamic composition adapted to the infant's needs. It contains bioactive lipids like cholesterol, typically transported by lactosomes, extracellular vesicles, and milk fat globules. However, classic cholesterol‐carrying lipoproteins have not been described in BM.
Gabriela Arenas, Andrea Morales, Andrea Leiva, Susana Contreras‐Duarte   +3 more
wiley   +1 more source

Characterising the plasma metabolome following high intensity interval exercise in continuous and intermittent hypoxia in overweight individuals

Experimental Physiology, EarlyView.
Abstract The aim of this work was to examine changes in the plasma metabolome in response to high‐intensity interval exercise (HIIE) performed under three distinct hypoxia protocols. On separate days, 18 inactive individuals with overweight completed a HIIE protocol in randomised conditions: normoxia (NEx‐NRec), normobaric hypoxia (inspired O2 fraction
Jacky Soo, Maartje Cox, Paul Goods, Olivier Girard, Louise Deldicque, Monique Ryan, Philipp Nitschke, Nathan Lawler, Timothy Fairchild   +8 more
wiley   +1 more source

Effect of sepsis on VLDL kinetics: responses in basal state and during glucose infusion

, 1985
The effect of gram-negative sepsis on the kinetics and oxidation of very low-density lipoprotein (VLDL) fatty acids was assessed in conscious dogs in the normal state and 24 h after infusion of live Escherichia coli.
M. J. Durkot, R. R. Wolfe, J. H. Shaw
core   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin

, 1994
Acute changes in very low-density lipoprotein (VLDL) triglyceride (TG) and VLDL apolipoprotein (apo) B production were examined in 11 healthy young males in response to insulin delivered either by the peripheral venous route or secreted directly by the ...
G. F. Lewis, L. Szeto, B. Weller, G. Steiner, B. Zinman, K. D. Uffelman   +5 more
core   +1 more source

An Anatomist's View on the Crosstalk Between the Liver and the Lung

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
The liver and the lung have a similar three‐dimensional and cellular architecture as well as functional communalities. The structural, functional, and pathophysiological interplay between both organs suggests the existence of an interorgan axis, the liver‐lung axis. Created in biorender.com.
Tanja Kloock, Julia Schipke, Christian Mühlfeld   +2 more
wiley   +1 more source