Results 11 to 20 of about 59,863 (274)
Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL [PDF]
Cardiovascular Research, 2003 The molecular mechanisms underlying the relationship between elevated plasma concentrations of triglyceride-rich lipoproteins and coronary artery disease remain uncertain. In the present work, we investigated the gene expression pattern and intracellular pathways in human endothelial cells incubated with very low density lipoproteins (VLDL).
Angela Pirillo +2 more
exaly +5 more sources
Intracellular Trafficking and Secretion of VLDL [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012 Steady increase in the incidence of atherosclerosis is becoming a major concern not only in the United States but also in other countries. One of the major risk factors for the development of atherosclerosis is high concentrations of plasma low-density lipoprotein, which are metabolic products of very low-density lipoprotein (VLDL).
Tiwari, Samata, Siddiqi, Shadab A.
openaire +4 more sources
Determinants of VLDL-triglycerides production
Current Opinion in Lipidology, 2012 Plasma free fatty acids (FFA) are major substrates for hepatic VLDL-triglycerides (VLDL-TG) production. In addition, it is a common belief that VLDL-TG production is a substrate driven process primarily determined by systemic FFA delivery. This review summarizes recent research of our understanding of the regulation of VLDL-TG production.Recent studies
Nielsen, Søren, Karpe, Fredrik
openaire +5 more sources
Journal of Lipid Research, 1999 The potential role of the very low density lipoprotein (VLDL) receptor in mediating VLDL-induced plasminogen activator inhibitor-1 (PAI-1) expression was studied in vitro.
Dudley Strickland +2 more
exaly +3 more sources
Measuring VLDL-triglyceride turnover in humans using ex vivo-prepared VLDL tracer [PDF]
Journal of Lipid Research, 2006 There has been more interest in VLDL-triglyceride (TG) kinetics during the last decade. Unfortunately, robust measurement methods are elaborate and not readily available.
Lars C. Gormsen +2 more
doaj +5 more sources
Journal of Lipid Research, 1998 We have previously shown that very low density lipoproteins (VLDL, Sf 60–400) from subjects with type IV hyperlipoproteinemia (HTG-VLDL) will induce appreciable cholesteryl ester accumulation in cultured macrophages (J774A.1).
Cynthia G Sawyez
exaly +3 more sources
Decreases in the serum VLDL-TG/non-VLDL-TG ratio from early stages of chronic hepatitis C: alterations in TG-rich lipoprotein levels. [PDF]
PLoS ONE, 2011 BACKGROUND: The liver secretes very-low-density lipoproteins (VLDLs) and plays a key role in lipid metabolism. Plasma total triglyceride (TG) level variations have been studied in patients with hepatitis C virus (HCV)-related chronic hepatitis (CH-C ...
Motoi Nishimura +10 more
doaj +2 more sources
Walking the VLDL tightrope in cardiometabolic diseases
Trends in Endocrinology & MetabolismVery-low-density lipoprotein (VLDL), a triglyceride-rich lipoprotein secreted by hepatocytes, is pivotal for supplying peripheral tissues with fatty acids for energy production. As if walking on a tightrope, perturbations in the balance of VLDL metabolism contribute to cardiometabolic dysfunction, promoting pathologies such as cardiovascular disease ...
Mindy Kim, Ze Zheng
openaire +4 more sources
Correlation of fasting lipid profile in non-diabetic CKD patients on conservative management
National Board of Examinations Journal of Medical Sciences, 2023 Background- Chronic kidney disease is emerging as a major chronic disease worldwide. There is surge in incidence of CKD in developing countries that is likely to pose a major problem in both health and economic sector.
Deepak Sha K +2 more
doaj +1 more source
Scramblases as Regulators of Autophagy and Lipid Homeostasis: Implications for NAFLD
Autophagy Reports, 2022 Equilibration of phospholipids between the two monolayers of the lipid bilayer of cellular membranes is mediated by scramblases acting as phospholipid shuttling proteins that are critical for cellular function, particularly during inter-organelle contact.
Allen Chen, Wen-Xing Ding, Hong-Min Ni
doaj +1 more source