Results 81 to 90 of about 2,675,526 (303)

Acute-phase HDL in phospholipid transfer protein (PLTP)-mediated HDL conversion.

, 2001
In reverse cholesterol transport, plasma phospholipid transfer protein (PLTP) converts high density lipoprotein(3) (HDL(3)) into two new subpopulations, HDL(2)-like particles and prebeta-HDL.
Sattler, W, Raynes, JG, Malle, E, Jari Metso, Ernst Malle, John G Raynes, Pirkko J Pussinen, Metso, J, Pussinen, PJ, Matti Jauhiainen, Jauhiainen, M, Wolfgang Sattler   +11 more
core   +1 more source

Everything in Moderation: Investigating the U-Shaped Link Between HDL Cholesterol and Adverse Outcomes [PDF]

, 2019
Despite historical evidence suggesting an inverse association between HDL cholesterol (HDL-C) and adverse cardiovascular events, pharmacological efforts to increase HDL-C and improve outcomes have not been successful.
Laurence S Sperling, Marc P Allard-Ratick, Pratik B Sandesara, Arshed A Quyyumi   +3 more
core   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Moderate dyslipoproteinemia induced inflammation and remodeling HDL and VLDL particles in post-renal transplant patients

Current Issues in Pharmacy and Medical Sciences, 2017
The aim of this paper was to examine whether moderate dyslipoproteinemia can cause an increase of hsCRP and LPO levels in Tx patients who had received immunosuppressive therapy and were without acute inflammatory diseases. Herein, the lipid levels, hsCRP,
Kimak Elzbieta, Baranowicz-Gaszczyk Iwona, Bialopiotrowicz Tomasz   +2 more
doaj   +1 more source

HUBUNGAN PROFIL LIPID DENGAN LAMA RAWATAN PASIEN STROKE ISKEMIK DI BADAN LAYANAN UMUM DAERAH RUMAH SAKIT UMUM CUT MEUTIA KABUPATEN ACEH UTARA

Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh, 2018
Stroke merupakan penyebab kematian ketiga di dunia dan merupakan penyebab kematian utama dengan peningkatan prevalensi yang signifikan setiap tahunnya di Indonesia.
Amelia Intan Saputri1, Meutia Maulina
doaj   +1 more source

MC-sample2-HDL-AM

, 2017
Admixture Mapping results for HDL-cholesterol: Mexico City sample
Esteban J Parra (7852496), Parra, Esteban J   +1 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

HDL GWAS

, 2023
Created on 24 Aug 2023 - 09:49 by Fergus HamiltonThis data includes the GWAS of HDL particle counts performed in UK Biobank on the full Nightingame NMR sample. Full details are in the paper.
Fergus Hamilton (16875693)
core   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Effect of Animal and Industrial Trans Fatty Acids on HDL and LDL Cholesterol Levels in Humans - A Quantitative Review [PDF]

, 2010
Background: Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart ...
Wanders Anne J., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Anne J. Wanders, Brouwer, I.A., Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +13 more
core   +2 more sources