Results 1 to 10 of about 342,740 (141)

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

HDL and cholesterol handling in the brain [PDF]

Cardiovascular Research, 2014
Cholesterol is an essential component of both the peripheral nervous system and central nervous system (CNS) of mammals. Brain cholesterol is synthesized in situ by astrocytes and oligodendrocytes and is almost completely isolated from other pools of cholesterol in the body, but a small fraction can be taken up from the circulation as 27 ...
C. Vitali, C. L. Wellington, L. Calabresi   +2 more
openaire   +4 more sources

Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]

, 2012
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Abt, Markus, Ballantyne, Christie M., Barter, Philip J., Brumm, Jochen, Chaitman, Bernard R., Colquhoun, David, Holme, Ingar M., Kallend, David, Leiter, Lawrence A., Leitersdorf, Eran, McMurray, John J. V., Mundl, Hardi, Nicholls, Stephen J., Olsson, Anders G., Schwartz, Gregory G., Shah, Prediman K., Tardif, Jean-Claude, The dal-OUTCOMES Investigators, Wright, R. Scott   +18 more
core   +2 more sources

Relation of hyperlipidemia in serum and loss of high density lipoproteins in urine in the nephrotic syndrome [PDF]

, 1987
The mechanism leading to hyperlipidemia in the nephrotic syndrome is not fully understood but may be related in part to loss of high density lipoproteins in the urine of patients with nephrosis.
Appel, Baxter, Baxter, Chopra, De Mendoza, Eggstein, Felts, Gherardi, Gherardi, Havel, Jüngst, Jüngst, Kashyap, Klahr, Lopes-Virella, Newmark, Ohta, Röschlau, Sachs, Sata, Tamm, Wada, Weichselbaum   +22 more
core   +1 more source

Which lipid measurement should we monitor? An analysis of the LIPID study [PDF]

, 2014
OBJECTIVES: To evaluate the optimal lipid to measure in monitoring patients, we assessed three factors that influence the choice of monitoring tests: (1) clinical validity; (2) responsiveness to therapy changes and (3) the size of the long-term ‘signal ...
Glasziou, Paul P., Irwig, Les, Kirby, Adrienne C., Simes, R. John, Tonkin, Andrew M.   +4 more
core   +1 more source

GALNT2 mRNA levels are associated with serum triglycerides in humans [PDF]

, 2016
Atherogenic dyslipidemia, characterized by high triglycerides (TG) and low high density lipoprotein (HDL)-cholesterol levels, is a feature of patients with insulin resistance, obesity, and type 2 diabetes (T2D) [1] and plays a major role in shaping the ...
Di Paola, Rosa, Mangiacotti, Davide, Marucci, Antonella, TRISCHITTA, VINCENZO   +3 more
core   +1 more source

Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. [PDF]

, 2019
BACKGROUND: The relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear.
Alver, M. (Maris), Amouyel, P. (Philippe), Bakker, S.J.L. (Stephan), Benjamin, E.J. (Emelia J.), Blankenberg, S. (Stefan), Bobak, M. (Martin), Brambilla, P. (Paolo), Brenner, H. (Hermann), Brunner, F.J. (Fabian J), Costanzo, S. (Simona), Dallongeville, J., de Lemos, J.A. (James A), Dobson, A. (Annette), Donfrancesco, C. (Chiara), Drygas, W. (Wojciech), Dullaart, R.P.F. (Robin P.F.), Dörr, M. (Marcus), Eliasson, M. (Mats), Engström, G., Ferrières, J. (Jean), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giles, G. (Graham), Grassi, G. (Guido), Hodge, A. (Allison), Hveem, K. (Kristian), Iacoviello, L. (Licia), Ikram, M.K. (M. Kamran), Ingelsson, M. (Martin), Jorgensen, T. (Torben), Jousilahti, P. (Pekka), Jääskeläinen, T. (Tuija), JöCkel, K.-H. (Karl-Heinz), Kavousi, M. (Maryam), Kee, F. (F.), Klotsche, J. (Jens), Koenig, W. (Wolfgang), Kontto, J. (Jukka), Kuulasmaa, K. (Kari), Lackner, K.J. (Karl), Landmesser, U. (Ulf), Leistner, D.M. (David M), Linneberg, A. (Allan), Lorenz, T. (Thiess), Lyngbakken, M.N. (Magnus N.), Magliano, D.J., Makarova, N. (Nataliya), Malyutina, S., Mathiesen, E.B. (Ellisiv), Meisinger, C. (Christa), Melander, O. (Olle), Metspalu, A. (Andres), Moitry, M. (Marie), Männistö, S. (Satu), Nauck, M. (Matthias), Niiranen, T. (Teemu), Nikitin, Y., Ojeda, F. (Francisco), Omland, T. (Torbjørn), Pajak, A. (Andrzej), Panagiotakos, D.B. (Demosthenes), Peters, A. (Annette), Pitsavos, C. (Christos), Riserus, U. (Ulf), Salomaa, V. (Veikko), Sans, S. (Susana), Schmidt, B. (Börge), Schöttker, B. (Ben), Shaw, J.E., Shea, S. (Steven), Signorini, S. (Stefano), Simons, L.A. (Leon), Söderberg, S. (Stefan), Tamosiunas, A. (Abdonas), Thorand, B. (Barbara), Tunstall-Pedoe, H. (Hugh), Twerenbold, R. (Raphael), Vasan, R.S. (Ramachandran Srini), Veronesi, G. (Giovanni), Völzke, H. (Henry), Waldeyer, C. (Christoph), Wannamethee, S.G. (Goya), Whincup, P.H. (Peter), Wild, P.S. (Philipp), Wilsgaard, T. (Tom), Woodward, M. (Mark), Zeller, T. (Tanja)   +86 more
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Alterations in Lipids and Adipocyte Hormones in Female-to-Male Transsexuals [PDF]

, 2010
Testosterone therapy in men and women results in decreased high-density lipoprotein cholesterol (HDL) and increased low-density lipoprotein cholesterol (LDL).
Basra, Sukhdeep S., Chandra, Prakash, Chen, Tai C., Tangpricha, Vin   +3 more
core   +5 more sources

Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20.000 middle-aged men and women in the Netherlands [PDF]

, 2012
We studied the associations of a difference in linoleic acid or carbohydrate intake with plasma cholesterol levels and risk of CHD in a prospective cohort study in the Netherlands. Data on diet (FFQ) and plasma total and HDL-cholesterol were available at
Boer, J.M.A., Geleijnse, J.M., Goede, J., de, Kromhout, D., Verschuren, W.M.M.   +4 more
core   +1 more source

The secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy. [PDF]

, 2013
Apolipoprotein A-I (ApoA-I) is the major protein component of high-density lipoprotein (HDL), and is critical for maintenance of cholesterol homeostasis.
Borja, Mark S, Budamagunta, Madhu S, Lagerstedt, Jens O, Oda, Michael N, Petrlova, Jitka, Voss, John C   +5 more
core   +1 more source