Results 101 to 110 of about 108,215 (261)

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Phase‐Retrieved High‐Throughput Multi‐Channel Simultaneous Surface Plasmon Resonance Detection

Laser &Photonics Reviews, EarlyView.
This work presents a new phase‐retrieval high‐throughput multi‐channel simultaneous SPR detection framework. By integrating an objective lens‐based coupling system with a rotation‐based ePIE (r‐ePIE) phase retrieval on the back focal planes, this framework significantly reduces the minimum required detection area to reveal localized information.
Mengqi Shen, Xiaoping Jiang, Shibiao Wei, Michael G. Somekh   +3 more
wiley   +1 more source

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

Dynamic performance of supercritical and transcritical CO2 cycle for combined heating and power from hot dry rock

Case Studies in Thermal Engineering
In recent years, the development and utilization of Hot Dry Rock (HDR) resources have garnered increasing attention, positioning HDR as a valuable new strategic resource.
Tailu Li, Kailun Zhou, Jie Li, Hua Yang
doaj   +1 more source

New advances in CRISPR/Cas-mediated precise gene-editing techniques

Disease Models & Mechanisms, 2023
Chris Richardson, Robert N. Kelsh, Rebecca J. Richardson   +2 more
doaj   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

The Dose Rate of Corpuscular Ionizing Radiation Strongly Influences the Severity of DNA Damage, Cell Cycle Progression and Cellular Senescence in Human Epidermoid Carcinoma Cells

Current Issues in Molecular Biology
Modern radiotherapy utilizes a broad range of sources of ionizing radiation, both low-dose-rate (LDR) and high-dose-rate (HDR). However, the mechanisms underlying specific dose-rate effects remain unclear, especially for corpuscular radiation. To address
Sergey S. Soroko, Dmitry V. Skamnitskiy, Ekaterina N. Gorshkova, Olga M. Kutova, Ismail R. Seriev, Anna V. Maslennikova, Evgeniy L. Guryev, Sergey V. Gudkov, Vladimir A. Vodeneev, Irina V. Balalaeva, Natalia Yu Shilyagina   +10 more
doaj   +1 more source

Improving HDR [PDF]

Nature Methods, 2019
openaire   +2 more sources

Urinary Fungal Microbiome and Associations With Overactive Bladder, Antibiotics and Therapy Response

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To characterize and compare the fungal urinary microbiome (“mycobiome”) in healthy women and those with overactive bladder (OAB), and secondarily compare the mycobiome by comorbidities, recent antibiotic exposure, and response to OAB therapy. Material and Methods DNA was isolated from urine of those with and without OAB and underwent
Glenn T. Werneburg, Michael D. Gross, Daniel R. Hettel, Madison Lyon, Sean McSweeney, Stacy H. Jeong, Jacob M. Knorr, Ava Adler, Thien Dang, Peace Orji, Suruchi Ramanujan, Emily Slopnick, Howard B. Goldman, Sandip P. Vasavada, Aaron W. Miller   +14 more
wiley   +1 more source

Subjective and objective evaluation of local dimming algorithms for HDR images [PDF]

, 2020
Chalmers, Alan, Debattista, Kurt, Duan, Lvyin, Lei, Zhichun   +3 more
core   +1 more source