Results 81 to 90 of about 49,453 (252)

CRISPR-Cas9-mediated homology-directed repair for precise gene editing

open access: yesMolecular Therapy: Nucleic Acids
CRISPR-Cas9-mediated homology-directed repair (HDR) is a versatile platform for creating precise site-specific DNA insertions, deletions, and substitutions. These precise edits are made possible through the use of exogenous donor templates that carry the
Hongyu Liao   +4 more
doaj   +1 more source

NTECARS: A Nonthermal Equilibrium CARS Spectra Fitting Code

open access: yesJournal of Raman Spectroscopy, EarlyView.
We present NTECARS, an open‐source code written in Julia for the calculation and fitting of CARS spectra under nonequilibrium conditions. Rovibrational distributions can be flexibly modeled and fitted for different use cases. The code currently implements CO2$$ \mathrm{C}{\mathrm{O}}_2 $$ and N2$$ {\mathrm{N}}_2 $$ molecules and is validated under ...
Christian A. Busch, Uwe Czarnetzki
wiley   +1 more source

Historic Columbia River Highway waterfall corridor timed-use permit pilot, Historic Columbia River Highway, Oregon

open access: yes, 2022
Title from PDF cover (viewed on January 19, 2023).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

MXenes in Next‐Generation Light‐Emitting Diodes: Innovations, Challenges, and Future Prospects

open access: yesLaser &Photonics Reviews, EarlyView.
This review provides a systematic and critical overview of MXene integration in LEDs from their synthesis strategies and electronic characteristics to their roles as electrodes, interlayers, and emissive materials. It also explores the emerging prospects and challenges for MXene‐enabled flexible, transparent, and intelligent display technologies that ...
Awais Ali   +9 more
wiley   +1 more source

Community gets you through: Success factors contributing to the retention of Aboriginal and Torres Strait Islander Higher Degree by Research (HDR) students

open access: yesStudent Success, 2018
This paper explores success factors contributing to the retention of Aboriginal and Torres Strait Islander Higher Degree by Research (HDR) students identified through a National Teaching Fellowship.
Katelyn Barney
doaj   +1 more source

Hydrologic Connectivity in the Edwards Aquifer between San Marcos Springs and Barton Springs during 2009 Drought Conditions

open access: yesTexas Water Journal, 2011
A study of water level data collected during the 2009 drought was conducted to determine if there is a hydrologic connection between the San Antonio segment and Barton Springs segment of the Edwards Aquifer.
Larry F. Land   +3 more
doaj  

A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp–Logan

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT A customizable, dynamic geometric phantom was developed to bridge the gap between simplistic static phantoms and highly realistic, complex 4D solutions. The phantom enables initial testing, helps detect implementation errors, and supports quantitative evaluation of new dynamic acquisition and reconstruction methods.
Tamás Hakkel   +4 more
wiley   +1 more source

Interactions entre les différents protagonistes d’un do [PDF]

open access: yesCinema & Território, 2018
La méthode du documentaire en lien avec les interactions possibles entre ses protagonistes (filmeur, filmé et spectateur) va dans un premier temps aider à définir les identités de ces participants à la construction du film documentaire. Puis, ce sont les
Natacha CYRULNIK
doaj  

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

Optimizing HDAC inhibitors to enhance HDR-associated CRISPR-Cas9 gene editing efficiency in vivo and in vitro

open access: yesHeliyon
Gene editing by CRISPR-Cas9 via homology-directed repair (HDR) offers precise and desirable modifications, but its low efficiency remains a challenge due to the dominance of the non-homologous end joining (NHEJ) pathway in DNA repair.
Jeong Woon Jang   +7 more
doaj   +1 more source

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