Results 81 to 90 of about 86,009 (325)
Progress and prospect of hot dry rock exploration and development
Shuiwen dizhi gongcheng dizhi, 2023 The exploitation and utilization of clean energy is a resource and environmental issue of common concern for global sustainable development. As a vital strategic and sustainable future energy, hot dry rock (HDR) has attracted more and more attention.
Dongguang WEN +14 more
doaj +1 more source
Predictable NHEJ Insertion and Assessment of HDR Editing Strategies in Plants
Frontiers in Genome Editing, 2022 Canonical CRISPR-Cas9 genome editing technique has profoundly impacted the fields of plant biology, biotechnology, and crop improvement. Since non-homologous end joining (NHEJ) is usually considered to generate random indels, its high efficiency mutation
K. Molla +3 more
semanticscholar +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Stereo Vision-Based High Dynamic Range Imaging Using Differently-Exposed Image Pair
Sensors, 2017 In this paper, a high dynamic range (HDR) imaging method based on the stereo vision system is presented. The proposed method uses differently exposed low dynamic range (LDR) images captured from a stereo camera.
Won-Jae Park +4 more
doaj +1 more source
Chromatin Modifications Orchestrate DNA Repair Pathway Choice: Epigenetics Strategies for Enhancing CRISPR–Cas9‐Mediated Knock‐In Efficiency [PDF]
Cell ProlifHistone modifications at CRISPR–Cas9‐induced DNA double‐strand breaks shape chromatin states and regulate DNA repair pathway choice. Transient epigenetic modulation may provide a promising strategy to enhance CRISPR–Cas9‐mediated gene knock‐in.
Chen X +9 more
europepmc +2 more sources
INTERNATIONAL JOURNAL OF MATHEMATICS AND COMPUTER RESEARCH, 2022 In this paper, we introduce the HDR-Nirmala index and the HDR-Nirmala exponential of a graph. We compute the HDR-Nirmala index and its corresponding exponential of chloroquine, hydroxychloroquine and remdesivir. Also we establish some properties of newly defined the HDR-Nirmala index.
openaire +2 more sources
Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome
Arthritis &Rheumatology, EarlyView.Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani +10 more
wiley +1 more source
Autism Research, EarlyView.ABSTRACT Cognitive tests that reflect the complexity of real‐world social interactions are essential for autism spectrum disorder (ASD)‐related clinical assessment and research. This study developed and adapted a Japanese version of the Reading the Mind in Films (RMF) test, which assesses mind‐reading ability through dynamic, multisensory, and context ...
Sayaka Kawakami +3 more
wiley +1 more source
A framework for HDR stereo matching using multi-exposed images
, 2013 Real world scenes that contain high dynamic range illumination present a special challenge for stereo matching algorithms due to a lack of texture in over- or under-exposed image regions. In this paper, we discuss possibilities for combining state-of-the-
Yoo, Hyunjin +2 more
core +2 more sources