Results 141 to 150 of about 30,786 (257)

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi   +11 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin   +9 more
wiley   +1 more source

Robust optimization of catheter positions and dwell times for HDR prostate brachytherapy

open access: yesMedical Physics, Volume 53, Issue 9, September 2026.
Abstract Background HDR prostate brachytherapy plans are sensitive to catheter placement uncertainty, as discrepancies between planned and delivered catheter positions can degrade target coverage and increase organ at risk dose. Current inverse planning methods optimize dwell times for a fixed implant geometry and do not account for geometric ...
Joseph B. Schulz   +3 more
wiley   +1 more source

Resistance of Botrytis cinerea to anilinopyrimidine fungicides: A novel ARMS‐PCR method for the detection of Bcpos5 mutations and characterization of resistance using CRISPR/Cas9 editing

open access: yesPest Management Science, Volume 82, Issue 9, Page 8189-8198, September 2026.
A TETRA‐primer amplification refractory mutation system polymerase chain reaction (T‐ARMS‐PCR) method was developed for simultaneous detection of the L412F/V and G408V mutations. L412F/V mutants were created using the CRISPR/Cas tool and no fitness cost was observed.
Georgios Sofianos   +3 more
wiley   +1 more source

HDR

open access: yesCliopsy, 2017
openaire   +1 more source

Technologies for engineering repetitive DNA

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Polish Brachytherapy Society clinical recommendations and expert consensus on radical high-dose-rate brachytherapy for prostate cancer. [PDF]

open access: yesJ Contemp Brachytherapy
Chyrek AJ   +24 more
europepmc   +1 more source

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