Results 141 to 150 of about 59,376 (244)
A randomized prospective comparison of intermittent methotrexate, methotrexate with leucovorin, and a methotrexate combination in head and neck cancer [PDF]
, 1981 Ronald C. DeConti, David Schoenfeld
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Machine Learning‐Enhanced Nanoparticle Design for Precision Cancer Drug Delivery
Advanced Science, EarlyView.Machine Learning (ML) is revolutionizing cancer nanomedicine by optimizing nanoparticle (NP) design and drug delivery. This review summarizes ML applications across all stages of NP drug delivery, along with a discussion of ongoing challenges and future directions.
Qingquan Wang +5 more
wiley +1 more source
Highlights in head and neck cancer [PDF]
, 2014 Abstract: During the 2020 annual ASCO meeting, the most recent advances in squamous cell carcinoma of the head and neck as well as nasopharyngeal carcinoma were discussed. First of all, weekly cisplatin proved to be non-inferior to three-weekly cisplatin in the postoperative setting. Next, several interesting studies in both locoregionally advanced and
openaire +7 more sources
Advanced Science, EarlyView.This study identifies a novel mechanism of nasopharyngeal carcinoma (NPC) cisplatin chemoresistance that DDAH1 expression is associated with cisplatin resistance in NPC cells primarily through the enhancement of the phosphoinositide Janus kinase 2 (JAK2)‐signal transducer and activator of transcription 3 (STAT3) pathway.
Jin‐Hao Yang +10 more
wiley +1 more source
Advanced Science, EarlyView.ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen +17 more
wiley +1 more source
Immunosuppressive substance in the sera of head and neck cancer patients [PDF]
, 1988 Noboru Yamanaka +3 more
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Advanced Science, EarlyView.Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li +20 more
wiley +1 more source
Induction therapy in head and neck cancer. A comparison of two regimens [PDF]
, 1986 Monica B. Spaulding +6 more
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Advanced Science, EarlyView.This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang +13 more
wiley +1 more source
Regional chemotherapy through a saphenous vein graft for the treatment of head and neck cancers [PDF]
, 1987 T. K. Choi, WI Wei, W. F. Lau, K. H. Lam
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