Results 41 to 50 of about 596,906 (359)

Head and Neck Cancer Trends in Semarang: An analysis of ASR and ASCR [PDF]

, 2015
Background: The sustainable incidence data of Head and Neck Cancer is poorly described in Indonesia. There was no large-scale epidemiological study of head and neck cancer in Indonesia, especially in Semarang and surrounding areas.
Hidanti, Mazaya Luthfia, PRASETYO, AWAL
core   +1 more source

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer. [PDF]

, 2017
Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown.
Barrett, John W, Black, Morgan, Boutros, Paul C, Datti, Alessandro, Fung, Kevin, Ghasemi, Farhad, Le, Carson Cao Son Huu, Leong, Hon Sing, Lowerison, Matthew R, MacNeil, Danielle, Mymryk, Joe S, Nichols, Anthony C, Palma, David A, Pinto, Nicole, Ruicci, Kara M, Vizeacoumar, Frederick, Winquist, Eric, Yoo, John   +17 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Developing a thyroid cancer differentiation state classification system using deep residual networks and metabolic signature profiling

npj Digital Medicine
We developed a deep residual network (ResNet) framework to classify thyroid cancer differentiation states by integrating multiomic data and interpretability analysis.
Yanzhi Zhang, Xiaoxue Du, Sijia Cai, Yiming Cao, Dan Zhao, Weibo Xu, Tian Liao, Ning Qu, Rongliang Shi, Qinghai Ji, Ben Ma, Yu Wang   +11 more
doaj   +1 more source

Herpesviruses in Head and Neck Cancers [PDF]

Viruses, 2019
Head and neck cancers arise from mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx and the etiology of head and neck cancers is complex and involves many factors, among which oncogenic viruses are also enumerated. Nevertheless, this type of cancers are among the most common cancers around the world.
Mikołaj Wołącewicz, Rafał Becht, Ewelina Grywalska, Paulina Niedźwiedzka-Rystwej   +3 more
openaire   +4 more sources

Psychosocial interventions for patients with head and neck cancer. [PDF]

, 2013
BACKGROUND: A diagnosis of head and neck cancer, like many other cancers, can lead to significant psychosocial distress. Patients with head and neck cancer can have very specific needs, due to both the location of their disease and the impact of ...
Aaronson, Bai, Bessell, Brink, Coleman, Cosco, Coyne, Doyle, Duffy, Duffy, Easterling, Fan, Fawzy, Fiegenbaum, Folkman, Frampton, Haman, Hammerlid, Harrison, Head, Holland, Holland, Humphris, Katz, Kroenke, Luckett, Maddalena, McLachlan, Mitchell, Norton, Norton, Petruson, Radloff, Rosenberg, Semple, Semple, Semple, Sharma, Sheikh, Spielberger, Spitzer, Vakharia, Veer, Vilela, Watson, Yongqin, Zigmond   +46 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

EPIDEMIOLOGICAL STUDY ON HEAD AND NECK MALIGNANCIES - A STUDY OF 150 CASES [PDF]

, 2013
OBJECTIVE: In the present study we investigate the head and Neck Malignancy cases presenting to the ENT department of our Hospital, and analyze the same to give inputs as to the incidence of head and neck malignancies, the symptoms and stage of ...
Gopalakrishnan, SankaraNarayanan, Kumar, Praveen   +1 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Comparison of Conventional Open Thyroidectomy and Endoscopic Thyroidectomy via Breast Approach for Papillary Thyroid Carcinoma

International Journal of Endocrinology, 2015
Purpose. The aim of this study was to evaluate the feasibility of endoscopic thyroidectomy via breast approach for papillary thyroid carcinoma (PTC). Methods. Between March 2008 and March 2013, 34 patients with PTC received endoscopic thyroidectomy (endo
Zhuo Tan, JiaLei Gu, QianBo Han, WenDong Wang, KeJing Wang, MingHua Ge, JinBiao Shang   +6 more
doaj   +1 more source