Results 51 to 60 of about 556,406 (311)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

PERBEDAAN SKOR GERIATRIC DEPRESSION SCALE PADA PASIEN USIA LANJUT DENGAN KANKER KEPALA DAN LEHER YANG BELUM DAN SEDANG MENJALANI RADIOTERAPI [PDF]

open access: yes, 2016
Background. There has been a constant rise in the elderly population number throughout the world, more so in the developing countries. This growth is paralleled with rapid increase in disease prevalence, head and neck cancer being one of them.
Saktini, Fanti   +2 more
core  

Treatment of head and neck cancer with photodynamic therapy: results after one year [PDF]

open access: yes, 2007
Photodynamic therapy (PDT) is a new and promising treatment modality for the treatment of malignant disease. This paper reports the preliminary experience of our group in the use of this therapy for the treatment of tumours arising in the head and neck ...
DeJode, ML   +4 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

A nomogram to predict postoperative overall and cancer specific survival in patients with primary parotid squamous cell carcinoma: a population based study

open access: yesScientific Reports
Primary parotid squamous cell carcinoma (pPSCC) is a rare salivary gland neoplasm. Due to the low incidence of pPSCC, there is a lack of clinical studies with large samples.
Xudong Liu   +7 more
doaj   +1 more source

Comparison of Conventional Open Thyroidectomy and Endoscopic Thyroidectomy via Breast Approach for Papillary Thyroid Carcinoma

open access: yesInternational Journal of Endocrinology, 2015
Purpose. The aim of this study was to evaluate the feasibility of endoscopic thyroidectomy via breast approach for papillary thyroid carcinoma (PTC). Methods. Between March 2008 and March 2013, 34 patients with PTC received endoscopic thyroidectomy (endo
Zhuo Tan   +6 more
doaj   +1 more source

Are the demographics for squamous cell cancer in the head and neck changing in the United Kingdom? [PDF]

open access: yes, 2007
Head and neck squamous cell carcinoma is well known to be more common in men than women. Smoking and alcohol are the key risk factors causing such malignancies and there are several publications which have suggested that the prevalence of these diseases ...
Hassan, MA   +3 more
core  

Life as an early career researcher: Ruth Bower [PDF]

open access: yes, 2016
Ruth Bower talks to Francesca Lake, Managing Editor: Ruth is currently researching head and neck cancer chemoradiotherapy regimens utilizing microfluidic technology to maintain and interrogate biopsies.
Bower, Ruth
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Exploring the dual role of B cells in solid tumors: implications for head and neck squamous cell carcinoma

open access: yesFrontiers in Immunology, 2023
In the tumor milieu of head and neck squamous cell carcinoma (HNSCC), distinct B cell subpopulations are present, which exert either pro- or anti-tumor activities.
Jiantong Bao   +5 more
doaj   +1 more source

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