Results 51 to 60 of about 315,615 (312)

MicroRNAs in Head and Neck Cancer [PDF]

International Journal of Dentistry, 2013
microRNAs (miRs) are small noncoding single-stranded RNAs, about 19–25 nucleotides long. They have been shown to be capable of altering mRNA expression; thus some are oncogenic or tumour suppressive in nature and are regulated by cellular and epigenetic factors.
Keziah John, Jennifer Wu, Bing-Wei Lee, Camile S. Farah   +3 more
openaire   +5 more sources

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Comparison of Conventional Open Thyroidectomy and Endoscopic Thyroidectomy via Breast Approach for Papillary Thyroid Carcinoma

International Journal of Endocrinology, 2015
Purpose. The aim of this study was to evaluate the feasibility of endoscopic thyroidectomy via breast approach for papillary thyroid carcinoma (PTC). Methods. Between March 2008 and March 2013, 34 patients with PTC received endoscopic thyroidectomy (endo
Zhuo Tan, JiaLei Gu, QianBo Han, WenDong Wang, KeJing Wang, MingHua Ge, JinBiao Shang   +6 more
doaj   +1 more source

Combination chemotherapy with taxane and platinum in patients with salivary gland carcinoma: a retrospective study of docetaxel plus cisplatin and paclitaxel plus carboplatin

Frontiers in Oncology, 2023
BackgroundDespite advances in precision medicine, most patients with recurrent or metastatic salivary gland carcinoma still need conventional chemotherapies, such as the combination of taxane and platinum.
Ryutaro Onaga, Tomohiro Enokida, Kazue Ito, Kazue Ito, Yuri Ueda, Yuri Ueda, Susumu Okano, Takao Fujisawa, Akihisa Wada, Akihisa Wada, Masanobu Sato, Hideki Tanaka, Naohiro Takeshita, Nobukazu Tanaka, Yuta Hoshi, Makoto Tahara   +15 more
doaj   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

A nomogram to predict postoperative overall and cancer specific survival in patients with primary parotid squamous cell carcinoma: a population based study

Scientific Reports
Primary parotid squamous cell carcinoma (pPSCC) is a rare salivary gland neoplasm. Due to the low incidence of pPSCC, there is a lack of clinical studies with large samples.
Xudong Liu, Jincai Xue, Fang Dong, Xingyue Wang, Youxin Tian, Qinjiang Liu, Jun Wang, Yunsheng Wang   +7 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Herpesviruses in Head and Neck Cancers [PDF]

Viruses, 2019
Head and neck cancers arise from mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx and the etiology of head and neck cancers is complex and involves many factors, among which oncogenic viruses are also enumerated. Nevertheless, this type of cancers are among the most common cancers around the world.
Mikołaj Wołącewicz, Rafał Becht, Ewelina Grywalska, Paulina Niedźwiedzka-Rystwej   +3 more
openaire   +4 more sources

An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces

Advanced Materials Interfaces, EarlyView.
Injectable electroconductive hydrogels enable soft, conformal, and stable bioelectronic interfaces for electroceutical therapies. A catechol‐modified hyaluronic acid/alginate/edge‐functionalized graphene platform combines wet adhesion, shear‐thinning injectability, tissue‐matched mechanics, and electrochemical functionality.
Ying Zhou, Peng Zheng, Beverley Cheung, Chien Yu Huang, Greg Ryder, Jonathan R Clark, D S Abdullah Al Maruf, Yi‐Hui Wu, Ming‐Dou Ker, Xufeng Huang, Gordon G Wallace, Xiao Liu   +11 more
wiley   +1 more source