Results 41 to 50 of about 556,406 (311)

Developing a thyroid cancer differentiation state classification system using deep residual networks and metabolic signature profiling

npj Digital Medicine
We developed a deep residual network (ResNet) framework to classify thyroid cancer differentiation states by integrating multiomic data and interpretability analysis.
Yanzhi Zhang, Xiaoxue Du, Sijia Cai, Yiming Cao, Dan Zhao, Weibo Xu, Tian Liao, Ning Qu, Rongliang Shi, Qinghai Ji, Ben Ma, Yu Wang   +11 more
doaj   +1 more source

Head and neck cancer in the elderly: a retrospective study over 10 years (1999 - 2008) [PDF]

, 2010
INTRODUCTION: Treatment of elderly patients is in many ways different from that for younger ones. The aim of the present study was to identify the particular characteristics and needs of elderly patients suffering from head and neck cancer.
Bredell, M, Grätz, K W, Kruse, Astrid L, Luebbers, Heinz T   +3 more
core   +1 more source

Herpesviruses in Head and Neck Cancers [PDF]

Viruses, 2019
Head and neck cancers arise from mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx and the etiology of head and neck cancers is complex and involves many factors, among which oncogenic viruses are also enumerated. Nevertheless, this type of cancers are among the most common cancers around the world.
Mikołaj Wołącewicz, Rafał Becht, Ewelina Grywalska, Paulina Niedźwiedzka-Rystwej   +3 more
openaire   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Long noncoding RNA RP11‐547D24.1 regulates proliferation and migration in papillary thyroid carcinoma: Identification and validation of a novel long noncoding RNA through integrated analysis of TCGA database

Cancer Medicine, 2019
Long noncoding RNAs (lncRNAs) are known to be key regulators of numerous biological processes, and substantial evidence supports that abnormal lncRNA expression plays a significant role in tumorigenesis and tumor progression.
Kai Guo, Lili Chen, Yunjun Wang, Kai Qian, Xiaoke Zheng, Wenyu Sun, Tuanqi Sun, Yi Wu, Zhuoying Wang   +8 more
doaj   +1 more source

Combination chemotherapy with taxane and platinum in patients with salivary gland carcinoma: a retrospective study of docetaxel plus cisplatin and paclitaxel plus carboplatin

Frontiers in Oncology, 2023
BackgroundDespite advances in precision medicine, most patients with recurrent or metastatic salivary gland carcinoma still need conventional chemotherapies, such as the combination of taxane and platinum.
Ryutaro Onaga, Tomohiro Enokida, Kazue Ito, Kazue Ito, Yuri Ueda, Yuri Ueda, Susumu Okano, Takao Fujisawa, Akihisa Wada, Akihisa Wada, Masanobu Sato, Hideki Tanaka, Naohiro Takeshita, Nobukazu Tanaka, Yuta Hoshi, Makoto Tahara   +15 more
doaj   +1 more source

EPIDEMIOLOGICAL STUDY ON HEAD AND NECK MALIGNANCIES - A STUDY OF 150 CASES [PDF]

, 2013
OBJECTIVE: In the present study we investigate the head and Neck Malignancy cases presenting to the ENT department of our Hospital, and analyze the same to give inputs as to the incidence of head and neck malignancies, the symptoms and stage of ...
Gopalakrishnan, SankaraNarayanan, Kumar, Praveen   +1 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

CBCT-to-CT synthesis with a single neural network for head-and-neck, lung and breast cancer adaptive radiotherapy

, 2019
Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung, and breast ...
Berg, Cornelis AT van den, Houweling, Anette C, Kotte, Alexis NTJ, Maspero, Matteo, Savenije, Mark HF, van Heijst, Tristan CF, Verhoeff, Joost JC   +6 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source