Results 71 to 80 of about 315,615 (312)

Postoperative irradiation for squamous cell carcinoma of head and neck: Retrospective comparison of accelerated radiochemotherapy and standard radiotherapy [PDF]

, 2000
Background: Comparison of accelerated radiochemotherapy (aRCT) and standard radiotherapy (sRT) in postoperative treatment after macroscopically complete resection of squamous cell cancers of head and neck.
Kiszel, Z., Busch, M., Kastenbauer, E., Panzer, Monika, Dühmke, Eckhart, Klaiber, R., Jund, R., Schaffer, Moshe, Winter, W.   +8 more
core   +1 more source

Salvage Surgery in Head and Neck Cancer

, 2021
Salvage surgery (SS) in head and neck cancer is considered a last resort treatment after failure of organ preservation treatments. It offers challenges to the patients and the surgeon. The outcome of SS is often uncertain in terms of survival and quality
C. René Leemans, Parmar, Sat, Leemans, C. René, Stijn van Weert, Sat Parmar, van Weert, Stijn   +5 more
core   +1 more source

Lived experience of having lymphedema after treatment of head and neck cancer: a qualitative study

BMC Cancer
Background Head and neck lymphedema (HNL) is an accumulation of interstitial protein-rich fluid. During treatment for head and neck cancer (HNC), lymphatic vessels may be removed or damaged, causing a decrease in the function of the lymphatic system ...
Coralie R. Arends, Lisette van der Molen, Michiel W.M. van den Brekel, Martijn M. Stuiver, Klaske van Sluis   +4 more
doaj   +1 more source

Skip metastasis in papillary thyroid carcinoma is difficult to predict in clinical practice

BMC Cancer, 2017
Background Cervical lymph node metastases are very common in papillary thyroid cancer (PTC), and typically spread in a predictable stepwise fashion in clinical practice. However, lateral lymph node metastasis (LLNM) without central lymph node metastasis (
Xilin Nie, Zhou Tan, Minghua Ge
doaj   +1 more source

Salvage Reconstructive Surgery During Nivolumab Therapy for a Patient With Hypopharyngeal Cancer

Clinical Medicine Insights: Case Reports, 2020
Objectives: Nivolumab, a fully IgG4-programmed death-1 inhibitor antibody, led to improved overall survival compared with single-agent therapy in patients with platinum-refractory recurrent head and neck cancers.
Nayuta Tsushima, Takeshi Shinozaki, Takao Fujisawa, Toshifumi Tomioka, Wataru Okano, Masakazu Ikeda, Makoto Tahara, Takuya Higashino, Ryuichi Hayashi   +8 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Local attitudes in the treatment of low prognosis head and neck squamous cell carcinoma [PDF]

, 2015
The incidence of head and neck carcinoma in Malta is 2.44 per 100,000 population, with 5-year survival rate of 20%. International studies have however shown that head and neck squamous cell carcinoma (HNSCC) carries an average 30% survival rate. The cost
Muscat, Kenneth, Borg Xuereb, Herman Karl, Dimech, Anthony   +2 more
core  

The potential impact of CT-MRI matching on tumor volume delineation in advanced head and neck cancer

, 1997
PURPOSE: To study the potential impact of the combined use of CT and MRI scans on the Gross Tumor Volume (GTV) estimation and interobserver variation.
Touw, A., Frank A. Pameijer, Ru, V. de, Lebesque, J.V., Coen Rasch, Keus, R.B., Rasch, C., Ronald Keus, Koops, W., Harry Bartelink, Muller, S., van Herk, M, Wim Koops, Van Herk, Marcel; id_orcid, Pameijer, F A, de Ru, V, Koops, W, de Ru, V., Muller, S, Bartelink, H., Pameijer, F. A., Lebesque, J. V., Saar Muller, Touw, A, Adriaan Touw, Joos V. Lebesque, Lebesque, J V, Keus, R, Keus, R., Herk, M. van, Bartelink, H, Vera de Ru, van Herk, M., Rasch, C, Pameijer, F.A., Marcel van Herk   +35 more
core   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Quality of life of patients treated surgically for head and neck cancer

, 1992
The quality of survival of 48 patients treated surgically for head and neck cancer was assessed using a problem-orientated self-administered questionnaire. The questionnaire was based on the European Organization for Research into the Treatment of Cancer
Howard, DJ, McCarthy, M, Jones, E, Lund, VJ, Greenberg, MP   +4 more
core