Results 31 to 40 of about 120,143 (300)
Dermoscopic and clinical features of head and neck melanoma [PDF]
Anais Brasileiros de Dermatologia, 2015 BACKGROUND:The dermoscopic criteria of extrafacial melanomas are well-known.OBJECTIVE:To determine the frequency of dermatoscopic findings in head and neck melanomas (HNM) and to assess the distinguishing dermoscopic criteria of facial and extrafacial ...
Fatma Pelin Cengiz +4 more
doaj +1 more source
ORAL PAPILLARY SQUAMOUS CELL CARCINOMA: CASE REPORT AND LITERATURE REVIEW
Revista Naval de Odontologia On Line, 2021 Papillary squamous cell carcinoma is a tumor that affects the upper aerodigestive tract, but rarely the oral cavity. The aim of this study is to report a case of oral papillary squamous cell carcinoma and to review the available literature. We
Lísia Daltro Borges Alves +4 more
doaj +1 more source
Опухоли головы и шеи, 2019 Most of the malignant neoplasms of the head and neck are represented by squamous cell carcinoma. 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in squamous cell carcinoma of the head and neck is applied for primary ...
О. D. Ryzhova +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
HYDROXYUREA: A RADIOSENSITIZER IN THE TREATMENT OF NEOPLASMS OF THE HEAD AND NECK [PDF]
American Journal of Roentgenology, 1969 Forty patients were treated in a double blind study utilizing Hydroxyurea. Those treated with Hydroxyurea, irradiation and surgery achieved complete eradication of tumor.The most notable contribution of Hydroxyurea appeared to be the extensive necrosis, radiation effect, and destruction beyond any recognition of tumor in lymph nodes.Forty-five cases ...
Robert G. Chambers, George J. Richards
openaire +3 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Development and Validation of a Pathomics Model Using Machine Learning to Predict Expression and Prognosis in Head and Neck Cancer [PDF]
Clinical and Experimental OtorhinolaryngologyObjectives. The necessity to develop a method for prognostication and to identify novel biomarkers for personalized medicine in patients with head and neck squamous cell carcinoma (HNSCC) cannot be overstated.
Weihua Wang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source