Results 51 to 60 of about 216,489 (301)

Photodynamic therapy in head and neck carcinomas: clinical and in vitro studies. [PDF]

, 2006
Despite the advances in diagnostic and therapeutic techniques, the outcome and survival of patients suffering from head and neck cancer has remained poor, primarily due to late detection, and the tendency of the disease to develop loco-regional ...
Sharwani, Abubakr, Sharwani, A.A.
core  

Management of adult soft tissue sarcomas of the head and neck

, 2010
Adult soft tissue sarcoma of the head and neck are rare and represent a heterogeneous group of tumours of different histological variants. Management of these neoplasms presents a great challenge.
de Bree, R., Eelco de Bree, de Bree, E., C. René Leemans, Bree, R. de, van der Waal, I., Remco de Bree, Waal, I. van der, Isaäc van der Waal, Bree, E. de, Leemans, C.R.   +10 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Epidemiology and Aetiology of Head and Neck Cancers

, 2011
Malignant neoplasms of the head and neck are among the most common in the world and constitute a major public health problem in most countries. Over 90% of these are squamous cell carcinomas arising in the mucous membranes of the upper aerodigestive ...
Hemantha K. Amarasinghe, Amarasinghe, Hemantha, Johnson, Newell, Newell W. Johnson   +3 more
core   +1 more source

Acetylsalicylic acid suppression of the PI3K pathway as a novel medical therapy for head and neck lymphatic malformations

, 2021
OBJECTIVES: Head and neck lymphatic malformations (HNLM) are caused by gain-of-function somatic mutations in PIK3CA. Acetylsalicylic acid (ASA/aspirin) is thought to limit growth in PIK3CA-mutated neoplasms through PI3K pathway suppression.
Zenner, Kaitlyn, Ganti, Sheila, Mitchell, Ryan M., Dobyns, William, Bly, Randall A., Whitlock, Kathryn B., Pham, Minh-Hang M., Bennett, James T., Dahl, John P., Jensen, Dana M., Cheng, Chi Vicky, Perkins, Jonathan A., Bonilla-Velez, Juliana   +12 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Primary Concurrent Chemoradiation in Head and Neck Cancers with Weekly Cisplatin Chemotherapy: Analysis of Compliance, Toxicity and Survival

International Archives of Otorhinolaryngology, 2017
Introduction Concurrent chemoradiation is the standard of care in inoperable locally advanced squamous cell head and neck cancers. The most widely accepted schedule of concomitant cisplatin is 100mg/m2 given on a 3 weekly basis but the optimal regime is ...
Muhammad Shahid Iqbal, Cheng Chaw, Josef Kovarik, Shahzeena Aslam, Aaron Jackson, John Kelly, Werner Dobrowsky, Charles Kelly   +7 more
doaj   +1 more source

ORAL PAPILLARY SQUAMOUS CELL CARCINOMA: CASE REPORT AND LITERATURE REVIEW

Revista Naval de Odontologia On Line, 2021
Papillary squamous cell carcinoma is a tumor that affects the upper aerodigestive tract, but rarely the oral cavity. The aim of this study is to report a case of oral papillary squamous cell carcinoma and to review the available literature. We
Lísia Daltro Borges Alves, Alessandra Laís Pinho Valente Pires, Tarsila de Carvalho Freitas Ramos, Márcio Campos Oliveira, Valéria Souza Freitas   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Sternocleidomastoid Pseudotumor Of Infancy: A Report Of Thirteen Cases

Journal of the Belgian Society of Radiology, 2012
Sternocleidomastoid tumor of infancy (SCMTI) is a rare cause of benign neck masses in neonates and infants. It has to be differentiated from other congenital space-occupying lesions in the cervical region.
I Hasni Bouraoui, N Arifa, M Gaha, W Kermani, K Mrad Dali, H Jemni, H Hmouda, K Tlili Graiess   +7 more
doaj   +1 more source