Results 71 to 80 of about 216,489 (301)

Surgical Management of a Multicentric Head-and-Neck Glomus Tumor: A Rare Case of Right Glomus Jugulare with Bilateral Carotid Body Tumors

Indian Journal of Vascular and Endovascular Surgery
Glomus tumors, also known as paragangliomas or chemodectomas, are usually slow–growing, benign, highly vascular tumors of neuroendocrine origin. Glomus tumors (paragangliomas) represent 0.6% of neoplasms of the head and neck and 0.03% of all neoplasms ...
Devender Singh, Manusrut Manusrut, Praveena Madavan, Shalini Aryala   +3 more
doaj   +1 more source

Development and Validation of a Pathomics Model Using Machine Learning to Predict Expression and Prognosis in Head and Neck Cancer [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. The necessity to develop a method for prognostication and to identify novel biomarkers for personalized medicine in patients with head and neck squamous cell carcinoma (HNSCC) cannot be overstated.
Weihua Wang, Suyu Ruan, Yuhang Xie, Shengjian Fang, Junxian Yang, Xueyan Li, Yu Zhang   +6 more
doaj   +1 more source

Chromosome 22q a frequent site of allele loss in head and neck carcinoma

, 2000
Background. Loss of heterozygosity (LOH) correlates with inactivated tumor suppressor genes. LOH at chromosome arm 22q has been found in a variety of human neoplasms, suggesting that this region contains a tumor suppressor gene(s) other than NF2 ...
Kowalski, Luiz P., Rogatto, Silvia Regina [UNESP], Bergamo, N. A., Reis, Patricia P. [UNESP], Rogatto, Silvia R. [UNESP], Zielenska, M., Squire, Jeremy A., Poli-Frederico, R. C., Bergamo, Nadia A. [UNESP], Reis, P. P., Zielenska, Maria, Poli-Frederico, Regina C. [UNESP], Kowalski, L. P., Squire, J. A., Rogatto, Silvia Regina   +14 more
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Nuchal Fibroma: An Uncommon Neck Mass

Bengal Journal of Otolaryngology and Head Neck Surgery, 2018
Introduction Nuchal fibroma or collagenosis nuchae is a rare benign tumour. It is a slow growing neoplasia of unknown etiogenesis, asymptomatic and of variegated histology. They are more common in males but our case was a female patient.
Soumyajit Das, Subhasish Mukherjee, Barun Sharma, Subash Tamang   +3 more
doaj  

Scoping review of head and neck neoplasms presenting with obstructive sleep apnoea: the importance of flexible nasendoscopy [PDF]

, 2020
Background Obstructive sleep apnoea (OSA) can be caused by neoplasms involving the upper aerodigestive tract. Currently, many of these patients have this diagnosis missed, as most adults diagnosed with OSA do not undergo adequate head and neck ...
Flatman, Samuel, Felipe Cardemil, Hayward, Nathan J., Cardemil Morales, Felipe, Nathan J. Hayward, Moore, Phillip, Phillip Moore, Samuel Flatman   +7 more
core   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Knowledge about head and neck cancer among adolescents

Brazilian Journal of Otorhinolaryngology
Objective: To assess knowledge about head and neck cancer among adolescents from private schools, aged between 13 and22 years. Methods: 200 questionnaires were applied among students, about the profile of adolescents and their knowledge about head and ...
Vinicius M. Vasconcellos, Leandro Luongo Matos, Flavio Carneiro Hojaij, Edevaldo Miguel Alves, Beatriz Costa N. Martins, Arthur C. Nava   +5 more
doaj   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Silent intruders: Hematolymphoid neoplasms revealed in the jaws: a series of three cases

Indian Journal of Pathology and Microbiology
The head and neck regions, rich in lymph nodes, are common initial sites for nodal and extranodal hematolymphoid neoplasms, particularly B-cell neoplasms. Lymphomas, including Hodgkin’s and non-Hodgkin’s types, range from indolent to aggressive and often
Trupti Jain, Sudeep Kumar, Shivangni Rajoria, R Keerthika, Akhilesh Chandra, Rahul Agarwal   +5 more
doaj   +1 more source