Results 31 to 40 of about 218,677 (332)

A 32-year-old man with plexiform schwannoma of the thyroid gland: a case report [PDF]

Journal of Yeungnam Medical Science
Plexiform schwannomas representing a rare subset, comprise 5% of all schwannomas. However, their occurrence in the thyroid gland is exceptionally rare. A 32-year-old male presented with an incidentally discovered, asymptomatic thyroid mass.
Il Rae Park, Min Chong Kim, Seung Min Chung, Si Youn Song   +3 more
doaj   +1 more source

The potential impact of CT-MRI matching on tumor volume delineation in advanced head and neck cancer

, 1997
PURPOSE: To study the potential impact of the combined use of CT and MRI scans on the Gross Tumor Volume (GTV) estimation and interobserver variation.
Touw, A., Frank A. Pameijer, Ru, V. de, Lebesque, J.V., Coen Rasch, Keus, R.B., Rasch, C., Ronald Keus, Koops, W., Harry Bartelink, Muller, S., van Herk, M, Wim Koops, Van Herk, Marcel; id_orcid, Pameijer, F A, de Ru, V, Koops, W, de Ru, V., Muller, S, Bartelink, H., Pameijer, F. A., Lebesque, J. V., Saar Muller, Touw, A, Adriaan Touw, Joos V. Lebesque, Lebesque, J V, Keus, R, Keus, R., Herk, M. van, Bartelink, H, Vera de Ru, van Herk, M., Rasch, C, Pameijer, F.A., Marcel van Herk   +35 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry

Acta Veterinaria Scandinavica, 2009
BackgroundHead and neck cancers (HNC) are relatively common and often very serious diseases in both dogs and humans. Neoplasms originating in the head and neck region are a heterogeneous group. HNC often has an unfavourable prognosis and the proximity of
L. B. Brønden, T. Eriksen, A. Kristensen   +2 more
semanticscholar   +1 more source

Exhaled breath analysis in the diagnosis of head and neck cancer

, 2019
Head and neck cancer (HNC) comprises a heterogeneous group of upper aerodigestive tract malignant neoplasms, the most frequent of which is squamous cell carcinoma. HNC forms the eighth most common cancer type and the incidence is increasing.
Nixon, I. J., Nixon, Iain, Almangush, A, Markus Metsälä, Youssef, Omar, Ferlito, Alfio, Vincent Vander Poorten, Metsala, M, Missak Haigentz, Jr., Omar Youssef, Vander, Poorten V, Juan P. Rodrigo, Mäkitie, Antti, Vander Poorten, V., Haigentz, Missak, Metsala, Markus, Rodrigo Tapia, Juan Pablo, Rodrigo, Juan P., Nixon, IJ, Almangush, A., Metsälä, M., Suvi Silén, Youssef, O, Silen, S, Nabil F. Saba, Silen, Suvi, Iain J. Nixon, Missak Haigentz, Ferlito, A., Alfio Ferlito, Silén, S., Makitie, AA, Saba, Nabil F., Nixon, Iain J., Mäkitie, A. A., Saba, N. F., Makitie, Antti A., Almangush, Alhadi, Antti A. Mäkitie, Youssef, O., Vander Poorten, Vincent, Rodrigo, JP, Saba, NF, Alhadi Almangush, Haigentz, MJ   +44 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A review of strategies to prevent periodontitis in patients with head and neck neoplasms undergoing chemotherapy

, 2022
In many countries, head and neck cancer incidence continues to rise. Treatment of head and neck cancer patients using chemotherapy has several oral side effects during and after treatment.
Bagherianlamraski, Mobina, Mobina Bagherianlamraski   +1 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

[Grading of head and neck neoplasms].

, 2016
Tumors of the head and neck form a heterogeneous group of benign and malignant neoplasms with significant differences in biological behavior and therapeutic strategies.
Agaimy, A;Weichert, W
core   +1 more source

SMARCB1 (INI‐1) and NUT immunoexpression in a large series of head and neck carcinomas in a Brazilian reference center

, 2020
Background: SMARCB1 (INI-1)-deficient carcinomas and NUT carcinomas are aggressive neoplasms, often affecting the sinonasal region. Not uncommonly, their diagnoses are made retrospectively. Methods: Through SMARCB1 (INI-1) and NUT immunomarkers, 643 head
Almeida, Luciana Y. [UNESP], Evânio V. Silva, Silva, Evânio V. [UNESP], Alfredo Ribeiro‐Silva, Luciana Y. Almeida, Tulio M. Ferrisse, Vanzolin, Bárbara F., Heitor A. Silveira, León, Jorge E., Neves-Silva, Rodrigo, Jorge E. León, Silveira, Heitor A. [UNESP], Colturato, Carla B. N., Andressa Duarte, Ribeiro-Silva, Alfredo, Rodrigo Neves‐Silva, Andreia Bufalino, Duarte, Andressa, Ferrisse, Tulio M. [UNESP], Carla B. N. Colturato, Bárbara F. Vanzolin, Bufalino, Andreia [UNESP]   +21 more
core   +1 more source