Results 31 to 40 of about 236,855 (311)

Outcomes and prognostic factors in parotid gland malignancies: A 10-year single center experience. [PDF]

, 2019
Objectives:To describe a 10-year single center experience with parotid gland malignancies and to determine factors affecting outcomes. Study Design:Retrospective review.
Bulbul, Mustafa, Deschler, Daniel G, Emerick, Kevin S, Khawaja, Ayaz, Lee, Hang, Lin, Derrick T, Parikh, Anuraag S, Puram, Sidharth V, Rocco, James W, Sethi, Rosh KV, Srikanth, Priya, Tjoa, Tjoson, Varvares, Mark A   +12 more
core   +1 more source

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Aydemir, Ü., Hartenstein, R., Munker, Reinhold, Pohlmann, H., Purmale, L., Reitmeier, M., Schorer, H.   +6 more
core   +1 more source

A 32-year-old man with plexiform schwannoma of the thyroid gland: a case report [PDF]

Journal of Yeungnam Medical Science
Plexiform schwannomas representing a rare subset, comprise 5% of all schwannomas. However, their occurrence in the thyroid gland is exceptionally rare. A 32-year-old male presented with an incidentally discovered, asymptomatic thyroid mass.
Il Rae Park, Min Chong Kim, Seung Min Chung, Si Youn Song   +3 more
doaj   +1 more source

Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer—the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis [PDF]

, 2014
Increased glucose uptake mediated by glucose transporters and reliance on glycolysis are common features of malignant cells. Hypoxia-inducible factor-1α supports the adaptation of hypoxic cells by inducing genes related to glucose metabolism.
Anna Krześlak, AP Demasi, AW Eckert, AW Eckert, BW Kim, C Zhang, CM Douglas, DE Burstein, DW Li, E Cadman, Ewa Brzezińska-Błaszczyk, Ewa Forma, FR Ayala, GL Semenza, H Kaida, H Kaida, Iwona Lewy-Trenda, J Xie, JL Roh, JL Thorne, K Müssig, K Starska, Katarzyna Starska, L Lan, L Zhang, M Kobayashi, M Mueckler, M Shimanishi, Magdalena Bryś, ML Schrijvers, O Koperek, OJ Kwon, Paweł Jóźwiak, R Cabanillas, R Ciampi, R Rashmi, S Kondo, S Ohba, S Zhou, SB Edge, SW Jing, SX Yan, T Yamada, W Fenske, W Ping, X Zhang, XH Chen, XH Wu, XP Sun, Y Cui, Y Kondo, YY Xu   +51 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Myxoid Neurothekeoma of the Nipple [PDF]

, 2011
Neurothekeomas are rare benign cutaneous neoplasms of nerve sheath origin. They are primarily found in the superficial soft tissue and are also known as dermal nerve sheath myxomas. They are commonly found on the upper extremities, head and neck followed
Indira, CS, Shivakumar, S, Thejaswini, MU, Vijaya Shankar, S   +3 more
core  

Nasopharyngeal Melanoma [PDF]

, 2018
Mucosal nasopharyngeal melanoma is a rare head and neck melanoma. Prognosis is poor (5-year overall survival rate of 10–30%) with high rates of metastases and local recurrence. Head and neck mucosal melanoma represents 0.8–3.7% of all melanomas and 0.03%
Calvieri, Stefano, Didona, Dario, Macrì, Giulia, Mercuri., Santo Raffaele, Paolino, Giovanni   +4 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Risk of critical illness among patients with solid cancers: a population-based observational study of 118,541 adults [PDF]

, 2015
Importance: Critical illness may be a potential determinant of cancer outcomes and geographic variations, but its role has not been described before. Objective: To determine the incidence of admission to intensive care units (ICUs) within 2 years ...
Kinsella, John, McLoone, Philip, Morrison, David S., Puxty, Kathryn, Quasim, Tara, Sloan, Billy   +5 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source