Results 151 to 160 of about 206,195 (300)

Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. Methods We conducted a multicenter retrospective study including 294 patients who underwent fibula free flap reconstruction and ...
Andrea Costantino, Bianca Festa, Filippo Marchi, Chung‐Kan Tsao, Raul Pellini, Luca Gazzini, Peter T. Dzięgielewski, Mario Ciniglio, Francesco Mazzola, Luca Calabrese, Antonio Sarno, Giampiero Parrinello, Linda Chow, Jyh‐Kwei Chen, Giorgio Peretti, Armando De Virgilio   +15 more
wiley   +1 more source

Greater Attention to Gingival Cancer and Floor of Mouth Cancer: Based on a Retrospective Analysis of Oral Cancer Across Different Subsites

Head &Neck, EarlyView.
ABSTRACT Background The gingiva and floor of the mouth are distinct subsites, and oral squamous cell carcinoma (OSCC) originating in these locations warrants further indepth understanding. Methods This study enrolled patients with OSCC from 2000 to 2020, and analyzed the clinicopathological characteristics.
Hao Li, Yi Ding, Yansheng Wu, Yan Fang, Xinhua Li, Weifeng Shi, Shaoshi Chen, Ailin Yang, Jin Zhang, Ruoyu Shi, Chao Jing, Xudong Wang, Yuansheng Duan   +12 more
wiley   +1 more source

Claudin-1 in Head and Neck Squamous Cell Carcinoma

Oncology
Introduction: The objective response rate to immunotherapy is limited in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) patients, whose prognosis is still dismal. Few prognostic factors are clinically available, mostly related to patient or disease characteristics. Gene expression signatures offer better prognostic abilities but are
Cavalieri, Stefano, Bergamini, Cristiana, Lenoci, Deborah, Ottini, Arianna, Lucchetta, Marta, Torchia, Erica, Licitra, Lisa, De Cecco, Loris   +7 more
openaire   +3 more sources

Efficacy of Multimodal Work‐Up of Head and Neck Squamous Cell Carcinoma Lymph Node Metastasis of Unknown Primary

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen, Roland M. Martens, Obaida Abdulrahman, Laura Peferoen, C. René Leemans, Gerben J. C. Zwezerijnen, Jan‐Jaap Hendrickx, Pim de Graaf   +7 more
wiley   +1 more source

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. [PDF]

, 2012
MicroRNAs are often associated with the pathogenesis of many cancers, including head and neck squamous cell carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to have a critical role in tumor cell survival, chemoresistance and HNSCC ...
Bourguignon, LYW, Earle, C, Krueger, K, Spevak, CC, Wong, G   +4 more
core  

Intraoperative Molecular Imaging Can Detect Large Nerve Perineural Invasion: A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) in head and neck squamous cell carcinoma (SCC) results in worse overall survival. Diagnosis requires resection and microscopic evaluation. Methods A 63‐year‐old male with persistent cT4aN0 p16‐positive SCC of the left base of tongue following chemoradiotherapy underwent salvage total glossectomy ...
Carleigh R. Burns, Aviva S. Mattingly, Kim Ely, Andreja Radevic, Nicole Meeks, Sydea Maria Ahmad Zaidi, Brandee Brown, Georgii Vasiukov, Michael Topf, Eben Rosenthal   +9 more
wiley   +1 more source

Skull Base Surgery in the Pediatric Population—The 2nd International Collaborative Study (1995–2015)

Head &Neck, EarlyView.
ABSTRACT Background The current study presents the efforts of a global collaborative group to review the management and outcomes of malignant tumors of the skull base in the pediatric population worldwide. Patients and Methods A total of 28 institutions contributed data on 3061 patients. From this, there were 64 pediatric patients (2.1%).
Dan M. Fliss, Omer J. Ungar, Helena Levyn, Cristina Valero, Dauren Adilbay, Alana Eagan, Junting Zheng, Mithat Gonen, Marc A. Cohen, Snehal Patel, Ian Ganly, Prathamesh Pai, Paolo Castelnuovo, Fang Ju Gao, Cesare Piazza, Piero Nicolai, Benedict J. Panizza, James Bowman, Catherine Barnett, Luiz P. Kowalski, Ronaldo N. Toledo, John DeAlmeida, Ian Witterick, Philippe Herman, Walter Fontanella, Gregorio Sanchez Aniceto, Sefik Hosal, Serdar Ozer, Subramania Iyer, Richard Harvey, C. Rene Leemans, Jan‑Jaap Hendrickx, Marcelo Figari, Luis Boccalatte, Ichi Nibu, Peter Clarke, Catherine Rennie, Yiming Zhu, Claudio Cernea, Sergio Goncalves, Rodney Schlosser, Fernando Dias, Zoukaa Sargi, Shahzada Ahmed, Wojciech Golusinski, Se Heon Kim, Shirley Y. Su, Shaan M. Raza, Franco DeMonte, Ehab Hanna, Jatin P. Shah   +50 more
wiley   +1 more source

Open Access [PDF]

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor ...
Andréia M Leopoldino, Carlos Curti, Eloiza H Tajara, Hamilton Cabral, J Silvio Gutkind, Lays M Sobral, Lewis J Greene, Lucas O Sousa, Ricardo D Coletta   +8 more
core  

Geographic and Institutional Patterns of Transoral Robotic Surgery in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Introduction Transoral robotic surgery (TORS) is increasingly used for oropharyngeal squamous cell carcinoma (OPSCC), yet national patterns of TORS availability for Medicare beneficiaries are not well defined. We characterized hospital type, geographic distribution, and market concentration of TORS.
Daniel Gilmore, Lauren R. Michelle, Xiaodan Hu, Stephen Y. Kang, Nolan B. Seim, Catherine T. Haring, Matthew O. Old, Amit Agrawal, Enver Ozer, Lauren E. Miller   +9 more
wiley   +1 more source

Oncological Outcomes of Salvage Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate oncological outcomes and their predictors following salvage oropharyngectomy. Methods This single‐center retrospective study included patients who underwent a salvage oropharyngectomy in an irradiated neck for recurrent or metachronous oropharyngeal squamous cell carcinoma (OPSCC) between 2014 and 2023.
Jade Saykaly, Sébastien Vergez, Agnès Dupret‐Bories, Anouchka Modesto, Benjamin Vairel, Jérôme Sarini, Aurore Siegfried, Ana Cavillon, Emilien Chabrillac   +8 more
wiley   +1 more source