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Head and neck squamous cell carcinoma [PDF]

Nature Reviews Disease Primers, 2020
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and larynx cancers are generally associated with tobacco consumption, alcohol abuse or both, whereas pharynx cancers are increasingly attributed to infection ...
Johnson, Daniel E, Burtness, Barbara, Leemans, C René, Lui, Vivian Wai Yan, Bauman, Julie E, Grandis, Jennifer R   +5 more
  +10 more sources

Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: Prevailing insights on molecular pathways, diagnosis, and nanomedicine treatment

Frontiers in Pharmacology, 2023
Head and neck squamous cell carcinoma is a disease that most commonly produce tumours from the lining of the epithelial cells of the lips, larynx, nasopharynx, mouth, or oro-pharynx. It is one of the most deadly forms of cancer.
Bedanta Bhattacharjee, Ayesha Farhana Syeda, Damanbhalang Rynjah, Shalam M. Hussain, Shekhar Chandra Bora, Padmanath Pegu, Ram Kumar Sahu, Jiyauddin Khan   +7 more
doaj   +1 more source

Early postoperative serum albumin levels as predictors of surgical outcomes in head and neck squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2022
Background: Malnutrition is a common issue in patients with head and neck squamous cell carcinoma and has a negative effect on surgical outcomes. Objective: We attempted to determine which malnutrition diagnostic variables can be used as predictors of ...
Tercio Guimarães Reis, Richard Alex Wesler Prudêncio da Silva, Eliane dos Santos Nascimento, José de Bessa, Júnior, Márcio Campos Oliveira, Antônio Sérgio Fava, Carlos Neutzling Lehn   +6 more
doaj   +1 more source

The identification of tumor antigens and immune subtypes based on the development of immunotherapies targeting head and neck squamous cell carcinomas resulting from periodontal disease

Frontiers in Oncology, 2023
Among cancer treatments, immunotherapy is considered a promising strategy. Nonetheless, only a small number of individuals with head and neck squamous cell carcinoma exhibit positive responses to immunotherapy.
Yangju Fu, Yongbo Zheng
doaj   +1 more source

Cutaneous Squamous Cell Carcinoma of the Head and Neck [PDF]

Journal of Skin Cancer, 2011
Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis.
Vivek V. Gurudutt, Eric M. Genden
openaire   +3 more sources

Tongue squamous cell carcinoma metastasis to percutaneous endoscopic gastrostomy site: A case report of an unusual cause of gastrointestinal bleeding

SAGE Open Medical Case Reports, 2023
Percutaneous endoscopic gastrostomy tubes are often placed in patients with head and neck malignancy for long-term nutritional support. Though rare, head and neck squamous cell carcinoma can metastasize to the percutaneous endoscopic gastrostomy tube ...
Hunza Chaudhry, Humzah Iqbal, Amitpaul Gill, Alakh Gulati, Juliana Yang   +4 more
doaj   +1 more source

Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]

Current Oncology Reports, 2018
Discussion of current strategies targeting the immune system related to solid tumors with emphasis on head and neck squamous cell carcinoma (HNSCC).This review will outline the current challenges with immunotherapy and future goals for treatment using these agents.Agents targeting immune checkpoint receptors (IR) such as program death 1 (PD1) have been
Moskovitz, Jessica, Moy, Jennifer, Ferris, Robert L.   +2 more
openaire   +2 more sources

Better outcome for parotid versus neck metastasis of head and neck cutaneous squamous cell carcinoma: a new report on reemerging data

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: Regional metastases of cutaneous head and neck squamous cell carcinoma occur in approximately 5 % of cases, being the most important prognostic factor in survival, currently with no distinction between parotid and neck metastasis. Objective:
Fábio Muradás Girardi, Vivian Petersen Wagner, Manoela Domingues Martins, Aliende Lengler Abentroth, Luiz Alberto Hauth   +4 more
doaj   +1 more source

Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]

Current Oral Health Reports, 2016
Head and neck squamous cell carcinoma has been found to be an immunosuppressive malignancy, with many defects in the host immune system contributing to the progression of disease. A greater understanding of these defects has lead to the identification and investigation of new therapeutic strategies, targeting immune system dysfunction in an effort to ...
Rebecca C, Hoesli, Jeffrey S, Moyer
openaire   +5 more sources

Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]

Hematology/Oncology Clinics of North America, 2015
Although head and neck squamous cell carcinoma has traditionally been considered to be a very immunosuppressive, or at least nonimmunogenic, tumor type, recent results from clinical studies of immune checkpoint blockade strategies have led to resurgence in the enthusiasm for immunotherapeutic approaches. Additional strategies for immunotherapy that are
David W, Schoppy, John B, Sunwoo
openaire   +4 more sources