Results 21 to 30 of about 121,885 (262)

PKM2 Modulation in Head and Neck Squamous Cell Carcinoma [PDF]

International Journal of Molecular Sciences, 2022
The enzyme pyruvate kinase M2 (PKM2) plays a major role in the switch of tumor cells from oxidative phosphorylation to aerobic glycolysis, one of the hallmarks of cancer. Different allosteric inhibitors or activators and several posttranslational modifications regulate its activity. Head and neck squamous cell carcinoma (HNSCC) is a common disease with
Verena Boschert, Jonas Teusch, Urs D. A. Müller-Richter, Roman C. Brands, Stefan Hartmann   +4 more
openaire   +3 more sources

Tim-3-expressing macrophages are functionally suppressed and expanded in oral squamous cell carcinoma due to virus-induced Gal-9 expression

Tumor Biology, 2017
Oropharyngeal head and neck squamous cell carcinoma is a common malignant tumor in the oral cavity. High-risk human papillomavirus 16 infection is a major cause of oropharyngeal head and neck squamous cell carcinoma development.
Jianfeng Dong, Lijun Cheng, Minchao Zhao, Xiangfeng Pan, Zhiqiang Feng, Dawei Wang   +5 more
doaj   +1 more source

Immunohistochemical expression of epidermal growth factor receptor (EGFR) in South Asian head and neck squamous cell carcinoma: association with various risk factors and clinico-pathologic and prognostic parameters

World Journal of Surgical Oncology, 2018
Background In this study, we intend to determine the immunohistochemical expression of EGFR in cases of head and neck squamous cell carcinoma and its association with prognostic clinico-pathologic features.
Atif Ali Hashmi, Zubaida Fida Hussain, Saher Aijaz, Muhammad Irfan, Erum Yousuf Khan, Samreen Naz, Naveen Faridi, Amir Khan, Muhammad Muzzammil Edhi   +8 more
doaj   +1 more source

Papillary Thyroid Carcinoma Coexistent with Oral Squamous Cell Carcinoma: A Case Report and Review of Literature [PDF]

Journal of Dentistry, 2019
Multiple primary tumors may develop in patients with head and neck squamous cell carcinoma. The coincidence of head and neck squamous cell carcinoma with papillary thyroid carcinoma is a rare finding.
Zohreh Jaafari-Ashkavandi, Hossein Danesteh, Haleh Keshvari   +2 more
doaj  

Correlation between T and N Stages of Head and Neck Squamous Cell Carcinoma

Journal of College of Medical Sciences-Nepal, 2015
Background and Objective: Squamous cell carcinoma of the head and neck region is a common pathological entity. Advanced primary lesion (T) and neck node metastasis (N) both are bad prognostic features for the carcinoma.
Krishna Koirala, Bimal Sinha, Dharma Kanta Baskota   +2 more
doaj   +1 more source

Single-cell sequencing reveals PHLDA1-positive smooth muscle cells promote local invasion in head and neck squamous cell carcinoma

Translational Oncology
Background: Smooth muscle cells within the tumor microenvironment play a crucial role in cancer progression. However, their involvement in the local invasion of head and neck squamous cell carcinoma remains poorly understood.
Bing Guo, Xutao Wen, Shun Yu, Jun Yang
doaj   +1 more source

An exceptional case of cutaneous metastasis of squamous cell carcinoma of the lip

Journal of Cancer Research and Practice, 2017
Majority of head and neck cancers are squamous cell carcinomas. Distant metastases of squamous cell carcinoma of the head and neck (HNSCC) occur at many sites, especially in the lung and bone. However, metastases to the skin are unusual and rare.
Vinita Trivedi, Muneer Abdul khalam, Manashi Ghosh, Richa Chauhan, Syeda Naseera   +4 more
doaj   +1 more source

Extracellular vesicles cargo from head and neck cancer cell lines disrupt dendritic cells function and match plasma microRNAs

Scientific Reports, 2021
Extracellular vesicles (EVs) are mediators of the immune system response. Encapsulated in EVs, microRNAs can be transferred between cancer and immune cells.
Elisangela de Paula Silva, Luciana Cavalheiro Marti, Flávia Maziero Andreghetto, Romário Oliveira de Sales, Martin Hoberman, Bárbara dos Santos Dias, Larissa Figueiredo Alves Diniz, Alessandro Marins dos Santos, Raquel Ajub Moyses, Otávio Alberto Curioni, Rossana Veronica Mendoza Lopez, Fabio Daumas Nunes, Eloiza Helena Tajara, Patricia Severino   +13 more
doaj   +1 more source

A composite score based on immune-related gene prognostic index and m6A risk score of head and neck squamous cell carcinoma

Frontiers in Genetics, 2023
Background: Immunotherapy has been demonstrated favorable in head and neck squamous cell carcinoma (HNSCC). Studies indicated that immune-related gene prognostic index (IRGPI) was a robust signature, and N6-methyladenosine (m6A) methylation had a ...
Yizhou Yang, Yizhou Yang, Yizhou Yang, Zeman Cai, Kaichun Huang, Mei Li, Xiao Wang, Xiao Wang, Xiao Wang, Yinbing Lin, Yinbing Lin, Yinbing Lin, Sijie Chen, Sijie Chen, Sijie Chen, Zhining Yang, Zhining Yang, Zhixiong Lin, Zhixiong Lin, Zhixiong Lin   +19 more
doaj   +1 more source

Invasive head and neck cutaneous squamous cell carcinoma: clinical and histopathological characteristics, frequency of local recurrence and metastasis [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: squamous cell carcinoma is the second most common type of skin malignancy and may evolve to regional lymph node and distant metastases. OBJECTIVE: The objective of this study was to evaluate patients with head and neck cutaneous squamous ...
Luiza Vasconcelos, Juliana Carneiro Melo, Hélio Amante Miot, Mariângela Esther Alencar Marques, Luciana Patricia Fernandes Abbade   +4 more
doaj   +1 more source