Results 11 to 20 of about 152,721 (288)
Head and neck squamous cell carcinoma [PDF]
Nature Reviews Disease Primers, 2020 Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and larynx cancers are generally associated with tobacco consumption, alcohol abuse or both, whereas pharynx cancers are increasingly attributed to infection ...
Johnson, Daniel E +5 more
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DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2-Mediated DNA Damage Response. [PDF]
Adv Sci (Weinh)DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Yang T +8 more
europepmc +2 more sources
Squamous cell carcinoma of the head and neck in the elderly [PDF]
Reports of Practical Oncology & Radiotherapy, 2013 The incidence of head and neck squamous cell carcinoma (HNSCC) peaks between the fifth and seventh decades of life. With prolongation of life expectancy, however, the proportion of elderly HNSCC patients is also increasing, which makes HNSCC in this life period an important issue for healthcare providers.
Gugić, Jasenka, Strojan, Primož
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Postoperative irradiation for squamous cell carcinoma of head and neck: Retrospective comparison of accelerated radiochemotherapy and standard radiotherapy [PDF]
, 2000 Background: Comparison of accelerated radiochemotherapy (aRCT) and standard radiotherapy (sRT) in postoperative treatment after macroscopically complete resection of squamous cell cancers of head and neck.
Kiszel, Z. +8 more
core +2 more sources
Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]
Current Oral Health Reports, 2016 Head and neck squamous cell carcinoma has been found to be an immunosuppressive malignancy, with many defects in the host immune system contributing to the progression of disease. A greater understanding of these defects has lead to the identification and investigation of new therapeutic strategies, targeting immune system dysfunction in an effort to ...
Rebecca C, Hoesli, Jeffrey S, Moyer
openaire +5 more sources
Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]
Hematology/Oncology Clinics of North America, 2015 Although head and neck squamous cell carcinoma has traditionally been considered to be a very immunosuppressive, or at least nonimmunogenic, tumor type, recent results from clinical studies of immune checkpoint blockade strategies have led to resurgence in the enthusiasm for immunotherapeutic approaches. Additional strategies for immunotherapy that are
David W, Schoppy, John B, Sunwoo
openaire +4 more sources
Cutaneous Squamous Cell Carcinoma of the Head and Neck [PDF]
Journal of Skin Cancer, 2011 Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis.
Vivek V. Gurudutt, Eric M. Genden
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A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]
, 2005 Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Wilkowski, R. +5 more
core +1 more source
The role of the chemokine receptor CXCR4 in oral squamous cell carcinoma metastasis [PDF]
, 2010 PhDOral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer worldwide. The greatest cause of mortality and surgical morbidity is due to the common spread of tumour cells from the primary lesion to the lymph nodes of the neck. This pathway is
Collier, Jonathan Marc
core +4 more sources
Immunotherapy for squamous cell carcinoma of the head and neck [PDF]
Japanese Journal of Clinical Oncology, 2020 Abstract Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against programmed cell ...
Tomoya Yokota +19 more
openaire +2 more sources