Background: Immunotherapy has been demonstrated favorable in head and neck squamous cell carcinoma (HNSCC). Studies indicated that immune-related gene prognostic index (IRGPI) was a robust signature, and N6-methyladenosine (m6A) methylation had a ...
Yizhou Yang +19 more
doaj +1 more source
A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Bernier J +25 more
core +1 more source
Preclinical models in head and neck squamous cell carcinoma
AbstractHead and neck cancer is the sixth most frequent cancer type. Drug resistance and toxicity are common challenges of the existing therapies, making the development of reliable preclinical models essential for the study of the involved molecular mechanisms as well as for eventual intervention approaches that improve the clinical outcome ...
Patricia Chaves +5 more
openaire +2 more sources
Background In this study, we intend to determine the immunohistochemical expression of EGFR in cases of head and neck squamous cell carcinoma and its association with prognostic clinico-pathologic features.
Atif Ali Hashmi +8 more
doaj +1 more source
Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue [PDF]
Five-year survival for patients with oral cancer has been disappointingly stable during the last decades, creating a demand for new biomarkers and treatment targets.
A Jemal +57 more
core +4 more sources
Papillary Thyroid Carcinoma Coexistent with Oral Squamous Cell Carcinoma: A Case Report and Review of Literature [PDF]
Multiple primary tumors may develop in patients with head and neck squamous cell carcinoma. The coincidence of head and neck squamous cell carcinoma with papillary thyroid carcinoma is a rare finding.
Zohreh Jaafari-Ashkavandi +2 more
doaj
Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
ABSTRACT Cancer stem cells (CSCs) are a small sub-population of cells within a tumor mass proficient of tumor initiation and progression. Distinguishing features possessed by CSCs encompass self-renewal, regeneration and capacity to differentiate.
Harish A Kumar +5 more
openaire +3 more sources
Background: Smooth muscle cells within the tumor microenvironment play a crucial role in cancer progression. However, their involvement in the local invasion of head and neck squamous cell carcinoma remains poorly understood.
Bing Guo, Xutao Wen, Shun Yu, Jun Yang
doaj +1 more source
An exceptional case of cutaneous metastasis of squamous cell carcinoma of the lip
Majority of head and neck cancers are squamous cell carcinomas. Distant metastases of squamous cell carcinoma of the head and neck (HNSCC) occur at many sites, especially in the lung and bone. However, metastases to the skin are unusual and rare.
Vinita Trivedi +4 more
doaj +1 more source
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé +14 more
core +1 more source

