Results 51 to 60 of about 152,721 (288)

A strategy for synergistic enhancement of immune circulation in head and neck squamous cell carcinoma by novel nucleic acid drug therapy and immunotherapy

Journal of Translational Medicine
Studies have shown that in the pathogenesis of head and neck squamous cell carcinoma, immune circulation obstruction caused by various factors including metabolic abnormalities, gene mutations, and matrix barrier, is a critical factor for the induction ...
Yangjian Hong, Yanyang Liu, Huize Shen, Bowen Li, Qinglin Li   +4 more
doaj   +1 more source

Cutaneous metastasis of carcinoma tongue: A rare case report

Journal of Dermatology and Dermatologic Surgery, 2019
Carcinoma of the oral cavity is one of the most common cancers of the head-and-neck region with frequent metastasis to internal organs, especially the lungs, liver, and bone.
Kuldeep Verma, Mudita Gupta, Anchana Gulati, Reena Kumari Sharma   +3 more
doaj   +1 more source

Correlation between PET/CT and CT in the staging prior to the treatment of head and neck squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: Head and neck squamous cell carcinoma is the seventh most common malignant tumor. The advances in treatment have improved the global survival rates in the past years, although the prognosis is still grave.
Fernando García-Curdi, Yolanda Lois-Ortega, Ana Muniesa-del Campo, Amaranta McGee-Laso, José Miguel Sebastián-Cortés, Héctor Vallés-Varela, Julio José Lambea-Sorrosal   +6 more
doaj   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma. [PDF]

Animal Model Exp Med
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Chen L, Sun S, Liu Y, Jiang L, Wu C, Liu T, Zhao Y, Liu Y, Liu L, Wang Q, Zheng X, Huang P.   +11 more
europepmc   +2 more sources

Local attitudes in the treatment of low prognosis head and neck squamous cell carcinoma [PDF]

, 2015
The incidence of head and neck carcinoma in Malta is 2.44 per 100,000 population, with 5-year survival rate of 20%. International studies have however shown that head and neck squamous cell carcinoma (HNSCC) carries an average 30% survival rate. The cost
Muscat, Kenneth, Borg Xuereb, Herman Karl, Dimech, Anthony   +2 more
core  

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Genetic Susceptibility to Head and Neck Squamous Cell Carcinoma [PDF]

JNCI Journal of the National Cancer Institute, 1996
In addition to influences of exposure to carcinogenic compounds, the development of cancer may depend on an individual intrinsic cancer susceptibility. Biomarkers for cancer susceptibility can be powerful additions to epidemiologic analyses.This multicenter, case-control analysis combines previously published data and new data to substantiate the value
Cloos, Jacqueline, Spitz, Margaret R., Schantz, Stimson P., Hsu, T. C., Zhang, Zuo Feng, Tobi, Hilde, Braakhuis, Boudewijn J.M., Snow, Gordon B.   +7 more
openaire   +4 more sources

Preclinical models in head and neck squamous cell carcinoma

British Journal of Cancer, 2022
AbstractHead and neck cancer is the sixth most frequent cancer type. Drug resistance and toxicity are common challenges of the existing therapies, making the development of reliable preclinical models essential for the study of the involved molecular mechanisms as well as for eventual intervention approaches that improve the clinical outcome ...
Patricia Chaves, María Garrido, Javier Oliver, Elisabeth Pérez-Ruiz, Isabel Barragan, Antonio Rueda-Domínguez   +5 more
openaire   +2 more sources

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma.

PLoS ONE, 2018
Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than in ...
Tuna Toptan, Marion G Brusadelli, Brian Turpin, David P Witte, Jordi Surrallés, Eunike Velleuer, Martin Schramm, Ralf Dietrich, Ruud H Brakenhoff, Patrick S Moore, Yuan Chang, Susanne I Wells   +11 more
doaj   +1 more source