Results 71 to 80 of about 143,284 (315)
Molecular Characterization of ‘p53 Family Network’ in Human Head and Neck Cancer and Anti-EGFR Therapy [PDF]
, 2008 Understanding of p53 family protein (p53, p63 and p73) networks in head and neck squamous cell carcinoma (HNSCC), can positively influence in cancer screening, diagnosis, treatment and prevention.
Sebastian, Sinto
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Basaloid squamous cell carcinoma of the head and neck: Our experience
Journal of Head & Neck Physicians and Surgeons, 2020 Basaloid squamous cell carcinoma (BSCC) of the head and neck is a distinctive variant of squamous cell carcinoma known for its basaloid appearance and aggressive behavior.
Jaimanti Bakshi +5 more
doaj +1 more source
Advanced Science, EarlyView.This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao +5 more
wiley +1 more source
Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G(2) delay and mitotic defects [PDF]
, 2013 Work by JP is funded by a Royal Society University Research Fellowship award. Experiments carried out by MBP were supported by the Department of Pathology, Albert Einstein College of Medicine / Montefiore Medical Center.The development of clinically ...
Parish, Joanna +9 more
core +1 more source
Easily detected signs of perineural tumour spread in head and neck cancer
Insights into Imaging, 2018 Perineural tumour spread (PNTS) in head and neck oncology is most often caused by squamous cell carcinoma. The most frequently affected nerves are the trigeminal and facial nerves. Up to 40% of patients with PNTS may be asymptomatic. Therefore, the index
Jan Willem Dankbaar +3 more
doaj +1 more source
Advanced Science, EarlyView.Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng +7 more
wiley +1 more source
CO2 lasers in the management of potentially malignant and malignant oral disorders [PDF]
, 2012 The CO2 laser was invented in 1963 by Kumar Patel. Since the early 1970s, CO2 laser has proved to be an effective method of treatment for patients with several types of oral lesions, including early squamous cell carcinoma.
Waseem Jerjes +5 more
core +1 more source
ASSESSMENT OF BLOOD SERUM PROTEOME IN PATIENTS WITH SQUAMOUS CELL HEAD AND NECK CARCINOMA
Сибирский онкологический журнал, 2016 We compared the serum proteome profiles of squamous cell head and neck carcinoma patients with metastases, without metastases and healthy volunteers using the combination of gradient gel-electrophoresis (1D-SDS PAGE) and mass-spectrometry.
G. V. Kakurina +4 more
doaj
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Photodynamic therapy in head and neck carcinomas: clinical and in vitro studies. [PDF]
, 2006 Despite the advances in diagnostic and therapeutic techniques, the outcome and survival of patients suffering from head and neck cancer has remained poor, primarily due to late detection, and the tendency of the disease to develop loco-regional ...
Sharwani, Abubakr, Sharwani, A.A.
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