Results 61 to 70 of about 143,284 (315)

Relationship between squamous cell carcinoma of the anterior two thirds of the tongue and removable denture use - a pioneer study in a Portuguese [PDF]

, 2011
The aim of the study was to determine whether there is any relationship between the presence of removable dentures and squamous cell carcinoma of the anterior two thirds of the tongue in a Portuguese population.
Chimenos-Küstner, Eduardo, Rui Alburqueque, Enrique Jané-Salas, Alburquerque, Rui, Marí Roig, Antonio, Antonio Marí-Roig, López López, José, 1958-, Marí-Roig, Antonio, Jané Salas, Enric, Chimenos Küstner, Eduardo, Santos, Jorge Rosa, Eduardo Chimenos-Küstner, Jorge Rosa Santos, Albuquerque, Rui, Jané-Salas, Enrique, López-López, Jose, Jose López-López   +16 more
core   +1 more source

Advanced Oropharyngeal Cancer Can Be Easily Missed During Esophagogastroduodenoscopy

European Journal of Case Reports in Internal Medicine, 2017
The case of an elderly man with an advanced oropharyngeal cancer that was missed during esophagogastroduodenoscopy is described. He was referred for endoscopic resection of superficial esophageal squamous cell neoplasms.
Kenta Hamada, Tomofumi Akasaka, Yasushi Yamasaki, Ryu Ishihara   +3 more
doaj   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

CT-PET guided target delineation in head and neck cancer and implications for improved outcome [PDF]

, 2010
Aim: Fifty percent of patients with squamous cell carcinoma of the Head and Neck develop loco-regional recurrence after treatment. Factors leading to this failure are most likely altered intra-tumoural glucose metabolism and increased hypoxia ...
Moule, R.N.
core  

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis [PDF]

, 2010
Background: Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires degradation of the extracellular matrix, which is fulfilled by membrane-associated ...
Olivier Gires, Muehlenweg Bernd, Pamela Zengel, Muehlenweg, Bernd, Gires, Olivier, Ramp, D., Gires, O., Alexander Berghaus, Gires Olivier, Mack, Brigitte, Zengel, Pamela, Zahler, Stefan, Muehlenweg, B., Diana Ramp, Stefan Zahler, Mack, B., Bernd Muehlenweg, Zahler, S., Berghaus Alexander, Mack Brigitte, Zengel, P., Suna Schmitz, Berghaus, Alexander, Schmitz, Suna, Schmitz, S., Ramp, Diana, Schmitz Suna, Zahler Stefan, Zengel Pamela, Brigitte Mack, Ramp Diana, Berghaus, A.   +31 more
core   +1 more source

Synergy of electrochemotherapy and immunotherapy in the treatment of skin squamous cell carcinoma of the head and neck

Oral and Maxillofacial Surgery Cases, 2023
Treatment of advanced-stage head and neck cutaneous squamous cell carcinoma is a challenge for maxillofacial surgeons, oncologists, and radiotherapists.
Ida Barca, Francesco Ferragina, Elvis Kallaverja, Maria Giulia Cristofaro   +3 more
doaj   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells [PDF]

, 2011
Background: Esophageal squamous cell carcinoma (ESCC) is often diagnosed at later stages until they are incurable. MicroRNA (miR) is a small, non-coding RNA that negatively regulates gene expression mainly via translational repression.
Yamashita, S., Nakayama Toshiyuki, Matsushima Kayoko, Nagayasu, T., Inoue, N., Hidaka, S., Ohtsuru Akira, Yibin Kang, Hayashi, T., Hajime Isomoto, Masaki Kunizaki, Shigeru Kohno, Mitsutake Norisato, Hidaka Shigekazu, Ohtsuru, A., Takeshi Nagayasu, Naoki Inoue, Nakao Kazuhiko, Mitsutake, N., Nakashima Masahiro, Yamaguchi Naoyuki, Gregory Philip A, Kang Yibin, Matsushima, K., Isomoto Hajime, Ujifuku Kenta, Goodall, G., Kenta Ujifuku, Machida Haruhisa, Nakayama, T., Yamaguchi, N., Korpal Manav, Tomayoshi Hayashi, Kang, Y., Norisato Mitsutake, Philip A Gregory, Naoyuki Yamaguchi, Yamashita Shunichi, Haruhisa Machida, et al., Nagayasu Takeshi, Kohno, S., Machida, H., Nakashima, M., Manav Korpal, Shigekazu Hidaka, Kunizaki, M., Inoue Naoki, Toshiyuki Nakayama, Shunichi Yamashita, Akira Ohtsuru, Goodall Gregory J, Gregory J Goodall, Korpal, M., Kazuhiko Nakao, Isomoto, H., Hayashi Tomayoshi, Gregory, P., Ujifuku, K., Kunizaki Masaki, Kayoko Matsushima, Masahiro Nakashima, Kohno Shigeru   +62 more
core   +2 more sources

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source