ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li +4 more
wiley +1 more source
Application of artificial intelligence in head and neck squamous cell carcinoma. [PDF]
Wang P, Tian J, Zheng G, Chen Y, Ren X.
europepmc +1 more source
Significance of SLC1A5 expression in head and neck squamous cell carcinoma: A bioinformatics and in-vitro analysis. [PDF]
Kaarunya S +3 more
europepmc +1 more source
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best +17 more
wiley +1 more source
Risk Factors for Suicide in Patients With Head and Neck Squamous Cell Carcinoma. [PDF]
Nishiguchi T +8 more
europepmc +1 more source
Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen +3 more
wiley +1 more source
Impact of Co‐Morbid Immunocompromise in HPV‐Associated Oropharyngeal Squamous Cell Carcinoma
Among patients with surgically resected Human Papillomavirus positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC), immunocompromised patients had significantly worse overall survival compared to the non‐compromised group; however, these exploratory findings should be interpreted cautiously.
Maxwell L. Weng +7 more
wiley +1 more source
Differentiation grade and combined positive score correlation in head and neck squamous cell carcinoma. [PDF]
Feng L +7 more
europepmc +1 more source
Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia +3 more
wiley +1 more source
Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest. [PDF]
Bae M +9 more
europepmc +1 more source

