Results 201 to 210 of about 206,966 (309)

Integrin α5β1 in head and neck squamous cell carcinoma: expression, mechanisms, and clinical implications. [PDF]

Am J Cancer Res
Wu B, Ma HZ, Shang JJ, Zhao XY, Wang ZY, Qiu LL.   +5 more
europepmc   +1 more source

Comment on: “Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone”

The Kaohsiung Journal of Medical Sciences, EarlyView.
Erkan Topkan, Efsun Somay, Ugur Selek
wiley   +1 more source

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

Precision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu, Xingyu Zhou, Jiao Xue, Xiaokang Zhang, Songbing Qin   +4 more
wiley   +1 more source

Enhanced CT‑based radiomics model to predict CD40LG expression and clinical prognosis in head and neck squamous cell carcinoma. [PDF]

Braz J Otorhinolaryngol
Fan L, Shi L, Yuan H, Wang Z, Wang J, Xian F, Mu Y.   +6 more
europepmc   +1 more source

Skeletal muscle status and malnutrition as predictors of short‐term radiotherapy response and oral mucositis in head and neck cancer

Precision Radiation Oncology, EarlyView.
Baseline muscle mass and malnutrition were not decisive for short‐term radiotherapy outcomes in advanced head‐and‐neck cancer, yet diminished hand‐grip strength signaled poorer tumor response. This suggests that functional muscle metrics may serve as an accessible, actionable biomarker warranting validation in larger longitudinal cohorts.
Haomiao Zhang, Xiaonan Hu, Junying Zhao, Mingxin Zhang, Yang You, Wencheng Shao, Lili Yu   +6 more
wiley   +1 more source

Context-dependent dysregulation of store-operated calcium channels in head and neck squamous cell carcinoma. [PDF]

PLoS One
Ghozlan H, Al-Malahmeh S, Al-Shboul O, Mistareehi AJ, Elsalem L.   +4 more
europepmc   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

CD3 and PD-L1 tissue expression have synergistic value in head and neck squamous cell carcinoma prognosis. [PDF]

Transl Oncol
Witzleben AV, Remark R, Idel C, Ribbat-Idel J, Krupar R, Schröck A, Klümper N, Doescher J, Sikora AG, Kors TA, Vahl JM, Brand M, Sonntag M, Brunner C, Hoffmann TK, Perner S, Gnjatic S, Laban S.   +17 more
europepmc   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source

Optimal timing of surgery in head and neck squamous cell carcinoma after neoadjuvant immunochemotherapy. [PDF]

Front Oncol
Seng H, Fan Y, Zhao R, Liu Y, Meng J, Wang Z, Chen Y, Shao S, Seng D.   +8 more
europepmc   +1 more source