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Introduction: Trauma brain injury is an emergency condition that requires immediate precise first aid to reduce mortality rates and prevent secondary complications.
Barkah Waladani+4 more
doaj +1 more source
The CRASH trial: the first large-scale, randomised, controlled trial in head injury. [PDF]
The global epidemic of head injuries is just beginning. Many are caused by road traffic crashes. It is estimated that, by 2020, road traffic crashes will have moved from its present position of ninth to third in the world disease burden ranking, as ...
Roberts, I
core +2 more sources
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
The effect of football (soccer) heading on gross and fine motor control in women
IntroductionHeading is an integral component of football, but concerns remain about its impact on brain health. This study examines the acute effects of heading on gross and fine motor control as a measure of the motor-cognitive function of women ...
Jac L. Palmer+10 more
doaj +1 more source
Investigation on risk prediction of pedestrian head injury by real-world accidents
Head injury is the most common and fatal injury in car-pedestrian accidents. Due to the lack of human test data, real-world accident data is useful for the research on the mechanism and tolerance of head injuries.
Fan Li+4 more
doaj +1 more source
Skull Flexure from Blast Waves: A Mechanism for Brain Injury with Implications for Helmet Design
Traumatic brain injury [TBI] has become a signature injury of current military conflicts, with debilitating, costly, and long-lasting effects. Although mechanisms by which head impacts cause TBI have been well-researched, the mechanisms by which blasts ...
Blackman, Eric G.+2 more
core +1 more source
Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao+34 more
wiley +1 more source
Sled acceleration control for low speed impact testing and transient response studies [PDF]
Whiplash Associated Disorder is the most common soft-tissue injury arising from low-speed car crashes (Siskind et al. 2013). To better understand whiplash injury mechanisms in the head-neck system, a sled was acquired.
LAPORTE, Sébastien+3 more
core +3 more sources
SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher+12 more
wiley +1 more source
Outcomes following childhood head injury : a population study [PDF]
Objectives: To identify outcomes following head injury (HI) amongst a population of children admitted to one hospital centre and compare outcomes between different severity groups. Methods:A postal follow-up of children admitted with HI to one NHS Trust,
Hawley, Carol+3 more
core +2 more sources