Results 111 to 120 of about 845,240 (304)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Development and flight tests of a gyro-less wing leveler and directional autopilot [PDF]
A gyro-less wing leveler and directional autopilot were developed and flight tested in a single-engine light airplane. The primary purpose of the project was to develop a simple, reliable, low-cost stability augmentation and autopilot system for light ...
Garner, H. D., Poole, H. E.
core +1 more source
On the horns of a dilemma [PDF]
, 2000 Illegality, as a concept, covers a multitude of sins and the differences that arise and the decisions of the courts are based on the principle of public policy.
Fletcher, Roland
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About the various contributions in Venus rotation rate and LOD
, 2011 % context heading (optional) {Thanks to the Venus Express Mission, new data on the properties of Venus could be obtained in particular concerning its rotation.} % aims heading (mandatory) {In view of these upcoming results, the purpose of this paper is ...
Barnes +31 more
core +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Active Target Defense Differential Game with a Fast Defender
, 2015 This paper addresses the active target defense differential game where an Attacker missile pursues a Target aircraft. A Defender missile is fired by the Target's wingman in order to intercept the Attacker before it reaches the aircraft.
Casbeer, David W. +2 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Heading in Female Soccer: A Scoping Systematic Review
SportsHeading is a key skill in soccer, and it is few investigated in females. Research on heading focused mostly on males and on young players. Data on females’ soccer players are sparse and it is difficult to draw firm conclusions.
Yinhao Shen +3 more
doaj +1 more source
Do it yourself: existentialism as punk philosophy [PDF]
, 2010 Existentialism is a notoriously difficult philosophy to explain. The thesis here is that comparing it with Punk Rock is a useful way in. They share a number of features: nihilistic, extreme, passionate, liberating, inclusive, amateur and violent, and ...
Hanscomb, S.
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