Results 111 to 120 of about 584,381 (304)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Motion Control System for USV Target Point Convergence

Sensors
The goal of this paper is to establish a motion control system for unmanned surface vehicles (USVs) that enables point-to-point tracking and dynamic positioning. This includes the heading control and path following control of USVs.
Jian Zhou, Hui Zhang, Kai Liu, Linhan Ma, Yanxia Yang, Zhanchao Fan   +5 more
doaj   +1 more source

Algorithm for fuel conservative horizontal capture trajectories [PDF]

A real time algorithm for computing constant altitude fuel-conservative approach trajectories for aircraft is described. The characteristics of the trajectory computed were chosen to approximate the extremal trajectories obtained from the optimal control
Erzberger, H., Neuman, F.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Variable output model-free adaptive heading control method for unmanned surface vehicle

Zhongguo Jianchuan Yanjiu
ObjectiveAiming at the uncertainty of model perturbation and external interference in unmanned surface vehicles (USVs), an improved model-free adaptive control (MFAC) method suitable for the heading control of USVs is proposed.
Yulei LIAO, Congcong CHEN, Tingpeng DU, Bo WANG, Ye LI   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Position and Attitude Control of Multi-Modal Underwater Robots Using an Improved LADRC Based on Sliding Mode Control

Sensors
This paper focuses on the control problems of a multi-modal underwater robot, which is designed mainly for the task of detecting the working environment in deep-sea mining.
Luze Wang, Yu Lu, Lei Zhang, Bowei Cui, Fengluo Chen, Bingchen Liang, Liwei Yu, Shimin Yu   +7 more
doaj   +1 more source

Adaptive Neural Backstepping Sliding Mode Heading Control for Underactuated Ships with Drift Angle and Ship-Bank Interaction. [PDF]

Comput Intell Neurosci, 2020
Han X.
europepmc   +1 more source

Personnel launch system autoland development study [PDF]

The Personnel Launch System (PLS) Autoland Development Study focused on development of the guidance and control system for the approach and landing (A/L) phase and the terminal area energy management (TAEM) phase.
Bossi, J. A., Langehough, M. A., Tollefson, J. C.   +2 more
core   +1 more source

A key variant in the cis-regulatory element of flowering gene Ghd8 associated with cold tolerance in rice. [PDF]

, 2019
Variations in the gene promoter play critical roles in the evolution of important adaptive traits in crops, but direct links of the regulatory mutation to the adaptive change are not well understood.
Fan, Kai, Gong, Rong, Wang, Peng, Xiong, Yin, Yang, Ying, Yu, Sibin   +5 more
core