Results 41 to 50 of about 14,560,647 (251)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
PlantsDeveloping early-heading wheat cultivars is an important breeding strategy to utilize light and heat resources, facilitate multiple-cropping systems, and enhance annual grain yield.
Binwen Tan +16 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2014 Heading time of substitution and near-isogenic lines (NILs) with Vrn-B1a and Vrn-B1c alleles was studied without vernalization and after 30-day vernalization in a greenhouse and in the field.
M. V. Emtseva +2 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Agriculture, 2022 Heading date is an essential agronomic trait that affects adaptability and yield in rice (Oryza sativa). HSFs (heat shock transcription factors) are a type of transcription factor that responds to environmental stress in organisms.
Tianzhen Liu +9 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
IEEE Access, 2019 In this paper, a soft-switching proximate time-optimal control (PTOC) is proposed based on the model-compensation extended state observer (ESO) and Takagi-Sugeno fuzzy switching, for the fast set-heading tracking of underactuated autonomous underwater ...
An Li +5 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Reliability of basic heading PPPs
, 2019 Purchasing power parities (PPPs) are compiled using a two-stage process. In the first stage, prices of items are aggregated without weights to obtain basic heading (BH) PPPs.
Hajargasht, Gholamreza +3 more
core +1 more source