Results 51 to 60 of about 14,560,647 (251)

Two-dimensional tunnel heading stability factors Fc, Fs and Fγ

open access: yes, 2020
This paper investigates the use of stability factors to estimate tunnel heading pressures. The primary method adopted is a conventional equation based on the soil property and stability factors, analogous to the bearing capacity factors (Nc, Ns and Nγ ...
Shiau, Jim, Al-Asadi, Fadhil
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Real-time Heading Estimation using Perspective Features [PDF]

open access: yes, 2013
There are a large number of commercially available quad-rotor helicopters available from various manufacturers. All of these systems rely on a low cost MEMS based inertial measurement system for stabilization and navigation.
Dean, James W.
core   +1 more source

Enhancement of Heading Accuracy for GPS/INS by Employing Average Velocity in Low Dynamic Situations

open access: yesIEEE Access, 2020
In this paper, we proposed an algorithm that improves the heading accuracy of the global positioning system (GPS)/inertial navigation system (INS) integrated system used in automobiles by manipulating INS velocity and GPS velocity measurements.
Min Jun Choi   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Comparisons of different soft control strategies in the evolvable-heading-shill scenario with ρn = 1 and θs = π/4.

open access: yes, 2018
Comparisons of different soft control strategies in the evolvable-heading-shill scenario with ρn = 1 and θs = π/4.
Caiyun Wang (179623), Jing Han (43038)
core   +1 more source

Minor Effects of 11 Dof Family Genes Contribute to the Missing Heritability of Heading Date in Rice (Oryza sativa L.)

open access: yesFrontiers in Plant Science, 2020
DNA binding with one finger (Dof) proteins are plant-specific transcription factors with important and diverse functions in seed germination, flowering time, and biotic and abiotic stresses.
Yong Huang   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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