Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Made in China: The international supply of illicit Semaglutide and weight-loss medicines online
Background: The use of GLP-1 medicines for weight-loss purposes is increasingly widespread. While these drugs are available as prescription medicines in the UK, there is an expansive illicit market for their supply operating online.
Luke A. Turnock +2 more
doaj +1 more source
Alcohol management plans and related alcohol reforms [PDF]
Indigenous Justice Clearinghouse Research Brief 16 provides an analysis of Alcohol Management Plans (AMPs); a relatively new instrument joining the extensive range of regulations relating to alcohol supply and consumption.
Alyson Brown +5 more
core
Innovation diplomacy caught between the two opposing logics of cooperation and competition: Case study on EU-China S&T cooperation in the field of solar PV. EL-CSID Working Paper Issue 2018/15 • April 2018 [PDF]
The purpose of this study is to test this question on the basis of a highly interesting illustrative case. It concerns the domain of the solar photovoltaics (solar PV) and the competition between the EU and China in this field.
Gehrt, Daniel
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
‘Pramana’ is one of the body parameter which needs to be examined under ‘Ayu laxanas’ (body chararacteristics) for assessment of strength of the body as well as for futuristic outcome of health and wellbeing. The Jyotish science is complimentary and contemporary to the Ayurvedic medical science.
openaire +1 more source
Consent, confidentiality and the ethics of PAR in the context of prison research [PDF]
Bailey, D, Ward, J
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Economic impact report on the New Zealand sport horse industry [PDF]
The aim of this research paper is to gain an understanding of the size and scope of the sport horse industry in New Zealand. The definition of the sport horse industry is that it comprises of all horses in New Zealand that are not being used for the
Akoorie, Michèle E.M., Matheson, Alex
core +1 more source

