Results 61 to 70 of about 108,315 (229)

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Improving Models of Care for Diabetes in Pregnancy: Experience of Current Practice in Far North Queensland, Australia

Frontiers in Public Health, 2019
Aims: To map health practitioners' experiences and describe knowledge regarding screening and management of Diabetes in Pregnancy (DIP) in Far North Queensland, Australia.Methods: Mixed methods including a cross-sectional survey (101 respondents) and 8 ...
Anna McLean, Anna McLean, Renae Kirkham, Sandra Campbell, Cherie Whitbread, Cherie Whitbread, Jennifer Barrett, Christine Connors, Jacqueline Boyle, Jacqueline Boyle, Alex Brown, Alex Brown, Jacqueline Mein, Mark Wenitong, H. David McIntyre, Federica Barzi, Jeremy Oats, Ashim Sinha, Louise Maple-Brown, Louise Maple-Brown   +19 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Recommendations of the Brazilian Society of Nephrology for regulating access to outpatient dialysis in the Brazilian Unified Health System [PDF]

Brazilian Journal of Nephrology
The increase in chronic kidney disease prevalence and its risk factors have pressured universal health systems to expand the supply of kidney replacement therapy (KRT - hemodialysis, peritoneal dialysis and kidney transplantation).
Farid Samaan, Fernanda Salomão Gorayeb-Polacchini, Alexandre Minetto Brabo, Paulo Henrique Fraxino, Fábio Humberto Ferraz, Ana Lydia Lédo de Castro Ribeiro Cabeça, René Scalet dos Santos Neto, Patrícia Ferreira Abreu, José A. Moura-Neto   +8 more
doaj   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Rol del estado en los ensayos clínicos

Revista Peruana de Medicina Experimental y Salud Pública
La regulación de los ensayos clínicos por el Estado es un proceso en constante cambio y adecuación, cuyo reto actual consiste en salvaguardar la seguridad de los participantes y equilibrar la carga administrativa.
Pilar Mazzetti, Gustavo Silva-Paredes, Mario Cornejo-Olivas   +2 more
doaj  

Patients with chronic kidney disease stage 3b: do general practitioners and nephrologists follow KDIGO guidelines? [PDF]

Brazilian Journal of Nephrology
Background: Appropriate referral and management of patients with chronic kidney disease (CKD) from primary care to nephrologists are essential to prevent disease progression and complications.
Juliana Gazzi Macedo, Alessandra Maciel Almeida, Helady Sanders-Pinheiro, Raquel Aparecida Fabreti-Oliveira   +3 more
doaj   +4 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source