Results 131 to 140 of about 14,647,476 (261)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Main consequences of alcoholism on health
Universidad Médica Pinareña, 2018 Aimed at describing the main consequences of alcoholism on health, a medical literature review was conducted, consulting a total of 29 references, from the sources as SciELO and PubMed.
Amanda Rodriguez Toribio +4 more
doaj
, 2007 171 p.The Health Systems in Transition (HiT) profiles are country-based reports that provide a detailed description of a health system and of policyinitiatives in progress or under development.
Merkur, Sherry +5 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Psychological Consequences of Parental Cancer On Children [PDF]
openThe aim of the thesis is to evaluate the psychological short-term and long-term consequences of parental cancer on children and possible interventions that have been reported in the existing research.
MARJANOVIC, TATJANA
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The World Health Organisation states that the health impacts of toxic chemical exposure, including plastics, during early life are a modern research priority.
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Health Care Workers at Risk [PDF]
Health-care workers are at extreme risk not only of psychological but somatic disorders as well. Present paper - while presenting the outline of the poor situation of physicians and health-care professionals - strives to enumerate circumstantial factors ...
György Kadocsa, Kornélia R. Lazányi
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