Results 151 to 160 of about 14,647,476 (261)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Health Consequences of Segregation and Disenfranchisement

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Girish L. Kalra, Karol E. Watson
doaj   +1 more source

Public health consequences of global climate change. A narrative review. [PDF]

open access: yesFront Cell Infect Microbiol
Apetrei-Pandrea A, Dascalu S.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Mental health consequences of Ukraine war

open access: yesTaiwanese Journal of Psychiatry, 2022
Amnuay Keebayoon   +2 more
doaj   +1 more source

Investing in health literacy: what do we know about the co-benefits to the education sector of actions targeted at children and young people?

open access: yes, 2016
27 p.Nearly half the European population are thought to have difficulties identifying, understanding and using health information. This has real and negative health consequences.
European Observatory on Health Systems and Policies   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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