Results 61 to 70 of about 6,730,818 (347)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Public health leadership education in North America

open access: yesJournal of Healthcare Leadership, 2010
Hideo Uno, Kenneth ZakariasenDepartment of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, AB, CanadaAbstract: Public health leadership is one of the priority disciplines public health professionals need to learn well if
Hideo Uno, Kenneth Zakariasen
doaj  

Impact of health education on adherence to clopidogrel and clinical effectiveness of antiplatelet treatment in patients after myocardial infarction

open access: yesFolia Medica Copernicana, 2015
Non-adherence rates to antiplatelet drugs in patients with acute myocardial infarction (AMI) range from 13% to 60%. We aimed to evaluate whether individual health education can improve adherence to treatment with clopidogrel in patients after AMI.
Aldona Kubica   +5 more
doaj   +1 more source

Whose knowledge is of most worth? The importance of listening to the voice of the learner. [PDF]

open access: yes, 2004
This paper discusses some of the data produced in the course of a research study that examined the perceptions that primary school aged children (7-13 year olds) had about their learning in health education.
Scratchley, Margaret J.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Elaboração de manuais de orientação para o cuidado em saúde Elaboración de manuales de orientación para el cuidado en salud The development of handbooks of health care guidelines

open access: yesRevista Latino-Americana de Enfermagem, 2005
Este artigo relata a experiência da autora na construção de manuais de orientação para o cuidado em saúde, no qual a descrição da metodologia utilizada é o foco principal.
Isabel Cristina Echer
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Formação em fisioterapia no Brasil: reflexões sobre a expansão do ensino e os modelos de formação Physical therapy education in Brazil: reflections on the expansion of teaching and training models

open access: yesHistória, Ciências, Saúde: Manguinhos, 2009
Discute a formação em fisioterapia no Brasil, problematizando aspectos da expansão do ensino, o campo de atuação e o perfil profissional. A abertura de novos cursos atingiu acelerada expansão a partir de 1997, porém de forma desregulada, com privatização
José Patrício Bispo Júnior
doaj   +1 more source

Educating for Indigenous health equity: An international consensus statement [PDF]

open access: yes, 2018
The determinants of health inequities between Indigenous and non-Indigenous populations include factors amenable to medical education’s influence, for example, the competence of the medical workforce to provide effective and equitable care to Indigenous ...
Calam, Betty   +15 more
core   +1 more source

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