Results 111 to 120 of about 6,426,006 (280)
Health evaluation: health assessment for people with ostomies
Objectives: to perform an evaluation study of the Ostomy Care Service in Brazil. Methods: a qualitative methodology was used, with a collaborative approach of the participants using the service, based on the seven elements proposed by Thurston and ...
Diana Mary Araújo de Melo Flach +4 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
As urbanization rapidly increases, the design of outdoor spaces in high-density urban environments has become crucial for promoting public health. This study investigates the health impacts of architecture-dominated outdoor spaces, particularly focusing ...
Yanyan Huang +3 more
doaj +1 more source
Parents and Children Together: Design and Implementation of Two Healthy Marriage Programs [PDF]
The Parents and Children Together (PACT) evaluation, conducted by Mathematica Policy Research for the Office of Research, Planning, and Evaluation, Administration for Children and Families (ACF), U.S. Department of Health and Human Services, is examining
Heather Zaveri, Scott Baumgartner
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Evaluating the impact of conditional cash transfer programs : lessons from Latin America [PDF]
Unlike most development initiatives, conditional cash transfer programs recently introduced in the Latin America and the Caribbean region have been subject to rigorous evaluations of their effectiveness.
Rawlings, Laura B., Rubio, Gloria M.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Vestibular Disorders Activities of Daily Living Scale (VADL) avalia o impacto da tontura e desequilíbrio corporal nas atividades cotidianas de indivíduos vestibulopatas. A escala contempla 28 atividades divididas em três dimensões (funcional, locomoção
Mayra Cristina Aratani +3 more
doaj

