Results 151 to 160 of about 6,426,006 (280)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Natural Experiments: An Efficient Tool for Population Respiratory Health Evaluation. [PDF]

Am J Respir Crit Care Med
Croft DP, Rich DQ.
europepmc   +1 more source

Abstracts : policy research working paper series - numbers 1936-1988 [PDF]

This paper contains abstracts of Policy Research Working Paper series Numbers 1936-1988.Health Economics&Finance,Health Monitoring&Evaluation,Achieving Shared Growth,Environmental Economics&Policies,Poverty ...
anonymous
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Opto electronic system for real time health evaluation of photovoltaic panels. [PDF]

Sci Rep
Mas'ud AA, Cuadra I, Ardila-Rey J, Barraza R, Sánchez-Squella A, Montoya OD, AlGarni HZ.   +6 more
europepmc   +1 more source

Fulfillment and Validity of the Kidney Health Evaluation Measure for People with Diabetes. [PDF]

Mayo Clin Proc Innov Qual Outcomes, 2023
Ferrè S, Storfer-Isser A, Kinderknecht K, Montgomery E, Godwin M, Andrews A, Dunning S, Barton M, Roman D, Cuddeback J, Stempniewicz N, Chu CD, Tuot DS, Vassalotti JA.   +13 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Adaptation of global One Health evaluation framework to municipal levels in Fukuoka, Japan. [PDF]

Infect Dis Poverty
Yokota F, Ning YS, Chen SN, Nomura H, Managi S, Liu JS, Zhang XX, Zhou XN, Shimizu S.   +8 more
europepmc   +1 more source

Economic and Welfare Effects of the Abolition of Health User Fees : Evidence from Uganda [PDF]

The authors use household level data for Uganda for 1999-2000 and 2002-03, before and after the abolition of user fees for public health services, to explore the effect of this policy on different groups'ability to access health services and morbidity ...
Deininger, Klaus, Mpuga, Paul
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source