Results 171 to 180 of about 7,977,848 (398)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Procedural fairness and the resilience of health financing reforms in Ukraine. [PDF]
Dzhygyr Y+4 more
europepmc +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
India's Health Initiative: Financing Issues and Options [PDF]
In response to the challenge of sustaining the health gains achieved in the better-performing states and ensuring that the lagging states catch up with the rest of the country, the Indian government has launched the National Rural Health Mission.
Deolalikar, Anil B.+2 more
core
Growing Pains for the Los Angeles Healthy Kids Program: Findings From the Second Evaluation Case Study (Apr 2008) [PDF]
Evaluates the program to provide health coverage to poor children ineligible for Medi-Cal or Healthy Families in terms of outreach, enrollment, and retention; benefits, service delivery, and access; financing and stability; and program ...
Brigette Courtot+3 more
core
Summary: Background: The World Health Assembly calls for elimination of viral hepatitis as a public health threat by 2030 (ie, −90% incidence and −65% mortality).
David Tordrup, MSc+9 more
doaj
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Convergence of divergence of OECD health care systems [PDF]
This article focuses on two major questions concerning the changing role of the state in the health care systems of OECD countries. Firstly, we ask whether major changes in the level of state involvement (in health care systems) have occurred in the past
Cacace, Mirella+4 more
core