Evaluation of spondyloarthritis-specific health utility based on ASAS health index (U-ASAS-HI) among the disease subtypes: an ancillary analysis from the ASAS-PerSpA study [PDF]
RMD OpenObjectives To compare the spondyloarthritis (SpA) specific universal health utility estimation from the ASAS health index (U-ASAS-HI) with the generic EuroQol-5D-3L (EQ-5D-3L) utility among SpA subtypes and to understand the contribution of health ...
Maxime Dougados +8 more
doaj +6 more sources
Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort [PDF]
RMD Open, 2023 Objective The objective of this study is to build a structural model visualising and quantifying the interrelationships of different disease outcomes with the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with ...
Sofia Ramiro +7 more
doaj +6 more sources
DEVELOPMENT AND VALIDATION OF THE CROHN'S DISEASE-HEALTH INDEX (CD-HI), A CLINICALLY-RELEVANT, DISEASE-SPECIFIC PATIENT-REPORTED OUTCOME MEASURE [PDF]
Gastroenterology, 2022 Abstract STUDY AIM The goal of this research is to develop and validate a novel, disease-specific patient-reported outcome measure (PROM) for use in clinical monitoring and therapeutic trials of Crohn’s Disease (CD).
Jamison Seabury +13 more
+15 more sources
AB0861 Health status in patients with axial spondyloarthritis (AXSPA) as determined by the assessment of spondyloarthritis international society health index (ASAS-HI) [PDF]
Annals of the Rheumatic Diseases, 2018 Background The ASAS-HI is a new instrument based in the International Classification of Functioning, Disability and Health to assess the impact of axSpA; ASAS-HI has been validated in Mexican patients. Objectives To investigate the status of health in Mexican patients with axSpA using the ASAS-HI Methods This is multicenter, cross-sectional study ...
R. Burgos-Vargas +16 more
openaire +2 more sources
Open Access Journal of Microbiology & Biotechnology, 2023 To assess the contamination load in vegetables and its possible human health hazards, heavy metals concentration (Cr, Cd, Cu, Pb, Ni, and Zn) in vegetables grown in the vicinity of the studied tannery area were determined. Health risk due to the consumption of vegetables was calculated from the metal concentration of the studied vegetables and the ...
Chamon AS
openaire +2 more sources
Health investments and well-being of middle-aged and elderly populations: a panel data analysis based on China [PDF]
Population Health MetricsBackground As the global population ages and life expectancies rise, improving the health and equity of middle-aged and older individuals has become a universal goal, especially with the economic benefits of the demographic dividend decreasing.
Di Wang +4 more
doaj +2 more sources
Development of a patient‐reported outcome measure for Alzheimer’s disease: the Alzheimer’s Disease‐Health Index (AD‐HI), a fully validated tool to bolster clinical trial and research infrastructure [PDF]
Alzheimer's & Dementia, 2023 AbstractBackgroundAs therapeutic advancements are made in Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI), it is important to have a fully validated, sensitive, and reliable disease‐specific patient‐reported outcome measure (PRO) to accurately measure changes in AD and MCI symptomatic disease burden. The U.S.
Spencer Rosero +8 more
openaire +2 more sources
Development and validation of a caregiver‐reported outcome measure for Alzheimer’s disease: the Alzheimer’s Disease Caregiver Reported‐Health Index (ADCR‐HI), a fully validated tool to bolster clinical trial and research infrastructure [PDF]
Alzheimer's & Dementia, 2023 AbstractBackgroundAs therapeutic advancements are made in the field of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI), it is important to have a fully validated, sensitive, and reliable, disease‐specific outcome measures that can accurately measure changes in AD and MCI symptomatic disease burden. The U.S. Food and Drug Administration has
Spencer Rosero +8 more
openaire +2 more sources
The Limb Girdle Muscular Dystrophy Health Index (LGMD-HI) [PDF]
Neuromuscular DisordersLimb girdle muscular dystrophy (LGMD) is a debilitating disease and the fourth most common muscular dystrophy. This study describes the development of the LGMD-Health Index (LGMD-HI). Participants were aged >18 years and recruited from three LGMD registries and GRASP-LGMD consortium.
Joy A. Stouffer +4 more
openaire +3 more sources
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2023 Objective: The identification of effective therapeutics for ALS necessitates valid and responsive outcome measures to track disease progression and therapeutic gain in clinical trial settings. The Amyotrophic Lateral Sclerosis-Health Index (ALS-HI) is a multifaceted, disease-specific patient-reported outcome measure (PRO) designed to measure ALS ...
Anika, Varma +17 more
openaire +3 more sources