Results 31 to 40 of about 50,490 (250)

Entomological Status Based on Vector Density Index and Transovarial Infection on Aedes Sp. Mosquito in Meteseh Village, Semarang City [PDF]

E3S Web of Conferences, 2020
Dengue Hemorrhagic Fever (DHF) is a disease caused by Dengue virus. In 2016, the number of DHF patients in areas of Health services of Rowosari was 247 cases, IR 289.6/100.000 populations and the highest number of the patients was from Meteseh Village ...
Martini Martini, Armen Zufri, Nissa Kusariana, Retno Hestiningsih, Sri Yuliawati, Atik Mawarni, Susiana Purwantisari   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gender difference in ASAS HI among patients with ankylosing spondylitis.

PLoS ONE, 2020
ObjectiveTo assess the associations of the Assessment of Spondyloarthritis International Society Health Index (ASAS HI) with gender and other factors in patients with ankylosing spondylitis (AS).MethodsFrom November 2017 to October 2018, we measured the ...
Hsin-Hua Chen, Yi-Ming Chen, Kuo-Lung Lai, Tsu-Yi Hsieh, Wei-Ting Hung, Ching-Tsai Lin, Chih-Wei Tseng, Kuo-Tung Tang, Yin-Yi Chou, Yi-Da Wu, Chin-Yin Huang, Chia-Wei Hsieh, Wen-Nan Huang, Yi-Hsing Chen   +13 more
doaj   +1 more source

Responsiveness of spondyloarthritis-specific health utilities based on the ASAS Health Index (U-ASAS-HI): an ancillary analysis from the ASAS-HI validation study

Rheumatology
Abstract Objectives To assess responsiveness of the spondyloarthritis (SpA)-specific universal health utility from the ASAS Health Index (U-ASAS-HI) compared with generic health utilities (EQ-5D-5L and SF-6D). Methods
Omar-Javier Calixto, Xenofon Baraliakos, Annelies Boonen, Wilson Bautista-Molano, Ivette Essers, Désirée van der Heijde, Juergen Braun, Uta Kiltz   +7 more
openaire   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Development of a health index for stranded marine tetrapods.

PLoS ONE
This study presents the development and validation of a Health Index (HI) to assess the overall health of stranded marine tetrapods (seabirds, sea turtles, and marine mammals).
André S Barreto, Karla R K Andrioli, Ana Paula F R L Bracarense, Marta J Cremer, Daphne W Goldberg, Guilherme Guerra-Neto   +5 more
doaj   +1 more source

Conicity Index Associated with Adult Hearing Impairment: A Cross-Sectional Study Based on the National Health and Nutrition Examination Survey (2001–2018)

Noise and Health
Objective: This study aimed to evaluate the association of conicity index (C-index), a marker of abdominal obesity, with hearing impairment (HI) in US adults using data from the National Health and Nutrition Examination Survey (NHANES).
Guifen Cai, Xiaoyan Xu, Xiaokun Li, Qiong Fang   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source