Results 91 to 100 of about 5,060,474 (306)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Data standard of the health information systems [PDF]

open access: yes, 2010
Semestrální projekt popisuje datový standard zdravotnických informačních systémů, jeho historii i nynější stav, formu, složení datových souborů a bloků. Datový standard jako takový slouží k předávání dat mezi zdravotnickými informačními systémy.
Sliž, Ladislav
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

A methodological proposal and tool support for the HL7 standards compliance in the development of health information systems [PDF]

open access: yes, 2017
Health information systems are increasingly complex, and their development is presented as a challenge for software development companies offering quality, maintainable and interoperable products.
Domínguez-Mayo, F.J   +7 more
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Interpreting the management of information systems security [PDF]

open access: yes, 1995
The management of adverse events within organisations has become a pressing issue as the perceptions of risk continue to heighten. However the basic need for developing secure information systems has remained unfulfilled.
Dhillon, Gurpreet
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Making More Efficient the Dissemination of the Information in the Field of Anti-Aging through Information Technology [PDF]

open access: yes
ICT have become extremely important because they allow everybody to participate at the Information Society, in spite of under-privileged personal or social situation.
Marilena IANCULESCU, Monica PARVAN
core  

Health information systems: international lessons [PDF]

open access: yes, 2001
At present Ireland lacks really effective and usable health information systems. The priorities listed in the draft ‘Information for Action’ report cannot be realised within the constraints of the existing systems. Our health information systems are not
Doyle, Sarah   +2 more
core  

Proposed A Job description for Nurses Using Health Information systems [PDF]

open access: diamond, 2023
Heba Mohamed   +2 more
openalex   +1 more source

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