Results 131 to 140 of about 134,023 (290)
Access, choice, and guidance in German Health Care: An account of health policy reforms since 2004 [PDF]
This paper discusses the influence of recent health care reform acts in Germany on choice, guidance and access from the perspective of patients, insured, insurers, and health care providers. Particular emphasis is put on health policy reforms since 2004,
Lisac, Melanie +3 more
core
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
The Evolution of Health Maintenance Organizations [PDF]
This thesis focuses on the development of Health Maintenance Organizations (HMOs) in the twentieth century. While the origins of the movement in the 1930s and 1940s are discussed, emphasis is also placed on the early 1970s and the 1990s, when HMOs ...
Paynter, Stewart
core
Background: Payment method is one of the most important control knobs in the health system. All organizations that mobilize funds for health sector must be decided: who should be paid? Why this money should be paid to them?
Sodabeh Vatankhah +4 more
doaj
Competition between health maintenance organizations and nonintegrated health insurance companies in health insurance markets. [PDF]
Baranes E, Bardey D.
europepmc +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
The Evolution of Health Maintenance Organizations. [PDF]
This thesis focuses on the development of Health Maintenance Organizations (HMOs) in the twentieth century. While the origins of the movement in the 1930s and 1940s are discussed, emphasis is also placed on the early 1970s and the 1990s, when HMOs ...
Paynter, Stewart.
core
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

