Results 141 to 150 of about 131,935 (244)

Understanding systemic barriers to AI-human collaboration integration for quality improvement in public health systems: a fuzzy DEMATEL analysis. [PDF]

Front Public Health
Almakayeel N.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Global Perspectives on Person-Centered Dementia Care: Results of an International Survey. [PDF]

J Appl Gerontol
Fazio S, Moczygemba W, Stratton L, Evans K, Weidner W, Banerjee S, Zimmerman S.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Protocol for the process evaluation of a mobile produce market intervention to increase fruit and vegetable consumption in lower-income communities: the Veggie Van Study. [PDF]

Front Public Health
Kasprzak C, Canizares A, Lally A, Vermont LN, Tumiel-Berhalter L, Raja S, Haynes-Maslow L, Ammerman A, Leone LA.   +8 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Oncology Organization and Oncologist Networks Under Medicare Advantage Plans.

JAMA Netw Open
Hu X, Kwon Y, Fan Q, Shi KS, Zheng Z, Zhao J, Warren JL, Yabroff KR, Zhang Z, Han X, Jiang C.   +10 more
europepmc   +1 more source

Sustainability and Localization of Health Infrastructure under CPEC 2.0: Toward a Self-Reliant Health System in Pakistan. [PDF]

Pak J Med Sci
Rui Y, Qiumei Q.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The burnout paradox. [PDF]

World Psychiatry
Bakker AB.
europepmc   +1 more source